Scientific Evidence Relevant to BHOC

Oxyglobin & Hemopure Evidence

Research on Oxyglobin, Hemopure and their historical development. Search by species, author, institution, journal and year.

192Publication records
10Species / model groups
101Author institutions
92Journals
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192 publication records

2024Rodent

Evaluating the Effects of Kidney Preservation at 10 °C with Hemopure and Sodium Thiosulfate in a Rat Model of Syngeneic Orthotopic Kidney Transplantation

Abou Taka M, Dugbartey GJ, Richard-Mohamed M, McLeod P, Jiang J, Major S, Arp J, O’Neil C, Liu W, Gabril M, Moussa M, Luke P, Sener A · International Journal of Molecular Sciences

Record details
Authors
Abou Taka M, Dugbartey GJ, Richard-Mohamed M, McLeod P, Jiang J, Major S, Arp J, O’Neil C, Liu W, Gabril M, Moussa M, Luke P, Sener A
Journal
International Journal of Molecular Sciences
Year
2024
Species / model
Rodent
Author institutions
London Health Sciences Center, University of Ghana, University of Western Ontario
Evidence type
Preclinical animal
DOI
10.3390/ijms25042210
PMID
38396887
Original citation
Abou Taka M, Dugbartey GJ, Richard-Mohamed M, et al. Evaluating the Effects of Kidney Preservation at 10 °C with Hemopure and Sodium Thiosulfate in a Rat Model of Syngeneic Orthotopic Kidney Transplantation. Int J Mol Sci. 2024 Feb 12;25(4):2210. doi: 10.3390/ijms25042210. PMID: 38396887; PMCID: PMC10889495.
2023

338.3: Utilization of oxygenated hemopure based University of Wisconsin solution during simulated procurement, back-benching, and graft implantation to minimize ischemic reperfusion injury in a rat liver transplantation simulated on pump

Kharga A, Chen H, Taggart M, Mojoudi M, Yeh H, Uygun K, Markmann JF · Transplantation

Record details
Authors
Kharga A, Chen H, Taggart M, Mojoudi M, Yeh H, Uygun K, Markmann JF
Journal
Transplantation
Year
2023
Evidence type
Preclinical animal
DOI
10.1097/01.tp.0000994584.62073.b9
Original citation
Kharga A, Chen H, Taggart M, Mojoudi M, Yeh H, Uygun K, Markmann JF. 338.3: Utilization of oxygenated hemopure based University of Wisconsin solution during simulated procurement, back-benching, and graft implantation to minimize ischemic reperfusion injury in a rat liver transplantation simulated on pump. Transplantation. 2023 Oct 1;107(10S2):147-8.

Malformed legacy source URL omitted; use the retained DOI or PubMed link

2023

PD31-06 THE EFFECT OF KIDNEY PRESERVATION AT 10°C WITH HEMOPURE AND HYDROGEN SULFIDE DONOR, SODIUM THIOSULFATE, IN A SYNGENEIC RAT RENAL TRANSPLANTATION MODEL

Taka MA, Sener A

Record details
Authors
Taka MA, Sener A
Journal
PD31-06 THE EFFECT OF KIDNEY PRESERVATION AT 10° C WITH HEMOPURE AND HYDROGEN SULFIDE DONOR, SODIUM THIOSULFATE, IN A SYNGENEIC RAT RENAL TRANSPLANTATION MODEL. The Journal of Urology
Year
2023
Evidence type
Preclinical animal
DOI
10.1097/ju.0000000000003324.06
Original citation
Taka MA, Sener A. PD31-06 THE EFFECT OF KIDNEY PRESERVATION AT 10° C WITH HEMOPURE AND HYDROGEN SULFIDE DONOR, SODIUM THIOSULFATE, IN A SYNGENEIC RAT RENAL TRANSPLANTATION MODEL. The Journal of Urology. 2023 Apr;209(Supplement 4):e902.
2022

Blood Component Requirements and Erythrocyte Transfusion and Mortality Related to Hemoglobin Deficit in Phase III Trial of Hemoglobin-Based Oxygen Carrier: HBOC-201

Jahr JS, Williams JP · American Journal of Therapeutics

Record details
Authors
Jahr JS, Williams JP
Journal
American Journal of Therapeutics
Year
2022
Evidence type
Human clinical evidence
PMID
35421008
Original citation
Jahr JS, Williams JP. Am J Ther. 2022 May-Jun 01;29(3):e279-e286. Epub 2022 Apr 14. PMID: 35421008.
2022

HBOC-201: History, Clinical Trials, and Path Forward

Record details
Year
2022
Evidence type
Review / Editorial / Policy
DOI
10.1007/978-3-030-95975-3_35
Original citation
Waters, J.H., Lim, J.C., Blanckenberg, J.M., Jahr, J.S. (2022). HBOC-201: History, Clinical Trials, and Path Forward. In: Liu, H., Kaye, A.D., Jahr, J.S. (eds) Blood Substitutes and Oxygen Biotherapeutics. Springer, Cham. https://doi.org/10.1007/978-3-030-95975-3_35
2022

Hemoglobin-Based Oxygen Carriers: Clinical Application of HBOC-201 As an Alternative to Red Blood Cells for Machine Perfusion in Liver Transplantation

Moein M, Ahmed M, Arafa F, Saidi RF · Surgery in Practice and Science

Record details
Authors
Moein M, Ahmed M, Arafa F, Saidi RF
Journal
Surgery in Practice and Science
Year
2022
Evidence type
Veterinary clinical / research
DOI
10.1016/j.sipas.2022.100120
Original citation
Moein M, Ahmed M, Arafa F, Saidi RF. Hemoglobin-Based Oxygen Carriers: Clinical Application of HBOC-201 As an Alternative to Red Blood Cells for Machine Perfusion in Liver Transplantation. Surgery in Practice and Science. 2022 Aug 20:100120.
2022

Hemoglobin-glutamer 250 (Bovine)[HBOC-201, Hemopure®] Clinical Use in South Africa and Comprehensive Review of Cardiac Outcomes and Risk/Benefit in Peer-Reviewed, Indexed Studies in Humans and Animal Models

Jahr JS, Tseng K, Brown AP, Dubé GP

Record details
Authors
Jahr JS, Tseng K, Brown AP, Dubé GP
Journal
NANOBIOTHERAPEUTIC BASED BLOOD SUBSTITUTES
Year
2022
Evidence type
Reviews, clinical context & policy
DOI
10.1142/9789811228698_0008
Original citation
Jahr JS, Tseng K, Brown AP, Dubé GP. NANOBIOTHERAPEUTIC BASED BLOOD SUBSTITUTES. 2022:207-47.
2022

Resuscitation of an exsanguinated obstetrics patient with HBOC-201: A case report

Barrett CD, Theodore S, Dechert T, et al · Transfusion

Record details
Authors
Barrett CD, Theodore S, Dechert T, et al
Journal
Transfusion
Year
2022
Evidence type
Human clinical evidence
DOI
10.1111/trf.16973
PMID
35748693
Original citation
Barrett CD, Theodore S, Dechert T, et al. Transfusion. 2022 Aug;62 Suppl 1:S218-S223. doi: 10.1111/trf.16973. Epub 2022 Jun 24. PMID: 35748693.
2021

New Applications of HBOC-201: A 25-Year Review of the Literature

Cao M, Zhao Y, He H, et al · Front Med (Lausanne)

Record details
Authors
Cao M, Zhao Y, He H, et al
Journal
Front Med (Lausanne)
Year
2021
Evidence type
Review / Editorial / Policy
DOI
10.3389/fmed.2021.794561
PMID
34957164
Original citation
Cao M, Zhao Y, He H, et al. Front Med (Lausanne). 2021 Dec 8;8:794561. doi: 10.3389/fmed.2021.794561. PMID: 34957164; PMCID: PMC8692657.
2020

A case study of 10 patients administered HBOC-201 in high doses over a prolonged period: outcomes during severe anemia when transfusion is not an option

Zumberg M, Gorlin J, Griffiths EA, Schwartz G, Fletcher BS, Walsh K, et al · Transfusion

Record details
Authors
Zumberg M, Gorlin J, Griffiths EA, Schwartz G, Fletcher BS, Walsh K, et al
Journal
Transfusion
Year
2020
Evidence type
Human clinical evidence
PMID
32358832
Original citation
Zumberg M, Gorlin J, Griffiths EA, Schwartz G, Fletcher BS, Walsh K, et al. Transfusion. 2020 May 1. [Epub ahead of print]
2020

Hemopure, HBOC-201, for Life Threatening Anemia in a Jehovah’s Witness

Nellis JR, Devinney MJ, Young CC (2020) Hemopure, HBOC-201, for Life Threatening Anemia in a Jehovah's Witness · Int J Blood Res Disord 7:052

Record details
Authors
Nellis JR, Devinney MJ, Young CC (2020) Hemopure, HBOC-201, for Life Threatening Anemia in a Jehovah's Witness
Journal
Int J Blood Res Disord 7:052
Year
2020
Evidence type
Pending full-text classification
DOI
10.23937/2469-5696/1410052
Original citation
Nellis JR, Devinney MJ, Young CC (2020) Hemopure, HBOC-201, for Life Threatening Anemia in a Jehovah's Witness. Int J Blood Res Disord 7:052. doi.org/10.23937/2469-5696/1410052

Malformed legacy source URL omitted; use the retained DOI or PubMed link

2020

When Every Drop of Blood Matters: HBOC 201 and Unconventional Ventilator Strategies to Tide Over Hemolytic Crisis

Chhabria MS, Sharma N, Tong Q, Manogna D, Sheppard TJ

Record details
Authors
Chhabria MS, Sharma N, Tong Q, Manogna D, Sheppard TJ
Journal
A1734-A1734)
Year
2020
Evidence type
Human clinical evidence
DOI
10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1734
Original citation
Chhabria MS, Sharma N, Tong Q, Manogna D, Sheppard TJ. CRITICAL CARE CASE REPORTS: HEMATOLOGY AND ONCOLOGY 2020 May (pp. A1734-A1734). American Thoracic Society.
2019

Anti-N and anti-Doa immunoglobulin G alloantibody-mediated delayed hemolytic transfusion reaction with hyperhemolysis in sickle cell disease treated with eculizumab and HBOC-201: case report and review of the literature

Unnikrishnan A, Pelletier JPR, Bari S, Zumberg M, Shahmohamadi A, Spiess BD, Michael MJ, Harris N, Harrell D, Mandernach MW · Transfusion

Record details
Authors
Unnikrishnan A, Pelletier JPR, Bari S, Zumberg M, Shahmohamadi A, Spiess BD, Michael MJ, Harris N, Harrell D, Mandernach MW
Journal
Transfusion
Year
2019
Evidence type
Review / Editorial / Policy
DOI
10.1111/trf.15198
PMID
30768787
Original citation
Anti-N and anti-Doa immunoglobulin G alloantibody-mediated delayed hemolytic transfusion reaction with hyperhemolysis in sickle cell disease treated with eculizumab and HBOC-201: case report and review of the literature. Unnikrishnan A, Pelletier JPR, Bari S, Zumberg M, Shahmohamadi A, Spiess BD, Michael MJ, Harris N, Harrell D, Mandernach MW. Transfusion. 2019 Feb 15. doi: 10.1111/trf.15198. [Epub ahead of print] PMID: 30768787 [PubMed - as supplied by publisher] Similar articles
2019Human · In vitro / laboratory

Freeze-dried plasma mitigates the dilution effects of a hemoglobin-based oxygen carrier (HBOC-201) in a model of resuscitation for hemorrhage and hemodilution

Meledeo MA, Peltier GC, McIntosh CS, Taylor AS, Bynum JA, Pusateri AE, Cap AP · J Trauma Acute Care Surg

Record details
Authors
Meledeo MA, Peltier GC, McIntosh CS, Taylor AS, Bynum JA, Pusateri AE, Cap AP
Journal
J Trauma Acute Care Surg
Year
2019
Species / model
Human, In vitro / laboratory
Author institutions
United States Army Institute of Surgical Research
Evidence type
In vitro & analytical evidence
DOI
10.1097/TA.0000000000002317
PMID
31246911
Original citation
Meledeo MA, Peltier GC, McIntosh CS, Taylor AS, Bynum JA, Pusateri AE, Cap AP. J Trauma Acute Care Surg. 2019 Jul;87(1S Suppl 1):S83-S90. doi: 10.1097/TA.0000000000002317. PMID: 31246911.
2019Human

Relative efficacies of HBOC-201 and PolyHeme to increase oxygen transport compared to blood and crystalloids

Dubé GP, Pitman AN, Mackenzie CF · Shock

Record details
Authors
Dubé GP, Pitman AN, Mackenzie CF
Journal
Shock
Year
2019
Species / model
Human
Author institutions
University of Maryland
Evidence type
Human clinical evidence
DOI
10.1097/shk.0000000000001058
PMID
29140831
Original citation
Relative Efficacies of HBOC-201 and Polyheme to Increase Oxygen Transport Compared to Blood and Crystalloids. "2017 Military Supplement". Dubé GP, Pitman AN, Mackenzie CF. Shock. 2017 Nov 14. doi: 10.1097/SHK.0000000000001058. [Epub ahead of print] PMID: 29140831 [PubMed - as supplied by publisher] Similar articles
2019

Selective aortic arch perfusion with fresh whole blood or HBOC-201 reverses hemorrhage-induced traumatic cardiac arrest in a lethal model of noncompressible torso hemorrhage

Hoops HE, Manning JE, Graham TL, et al · J Trauma Acute Care Surg

Record details
Authors
Hoops HE, Manning JE, Graham TL, et al
Journal
J Trauma Acute Care Surg
Year
2019
Evidence type
Pending full-text classification
DOI
10.1097/TA.0000000000002315
PMID
31348400
Original citation
Hoops HE, Manning JE, Graham TL, et al. J Trauma Acute Care Surg. 2019 Aug;87(2):263-273.

The imported PMID 31211744 was invalid. Corrected to PMID 31348400 and DOI 10.1097/TA.0000000000002315 after matching the title, authors, year and journal pages against PubMed on 11 October 2026.

2019

Successful management of the potentially fatal hyperhaemolysis syndrome of sickle cell anaemia with a regimen including bortezomib and Hemopure

Epstein SS, Hadley TJ · J Clin Pharm Ther

Record details
Authors
Epstein SS, Hadley TJ
Journal
J Clin Pharm Ther
Year
2019
Evidence type
Pending full-text classification
PMID
31237703
Original citation
Epstein SS, Hadley TJ. J Clin Pharm Ther. 2019 Oct;44(5):815-818. Epub 2019 Jun 25.
2019

The efficacy of HBOC-201 in ex situ gradual rewarming kidney perfusion in a rat model

Mahboub P, Aburawi M, Karimian N, et al · Artif Organs

Record details
Authors
Mahboub P, Aburawi M, Karimian N, et al
Journal
Artif Organs
Year
2019
Evidence type
Preclinical animal
DOI
10.1111/aor.13534
Original citation
Mahboub P, Aburawi M, Karimian N, et al. Artif Organs. 2020 Jan;44(1):81-90. Epub 2019 Aug 1.
2019Human

Users Guide to Pitfalls and Lessons Learned about HBOC-201 during Clinical Trials, Expanded Access and Clinical Use in 1,701 Patients

Mackenzie CF, Dubé GP, Pitman A, Zafirelis M · Shock

Record details
Authors
Mackenzie CF, Dubé GP, Pitman A, Zafirelis M
Journal
Shock
Year
2019
Species / model
Human
Author institutions
University of Maryland
Evidence type
Reviews, clinical context & policy
DOI
10.1097/shk.0000000000001038
PMID
29076972
Original citation
Users Guide to Pitfalls and Lessons Learned about HBOC-201 During Clinical Trials, Expanded Access, and Clinical use in 1,701 Patients. Mackenzie CF, Dubé GP, Pitman A, Zafirelis M. Shock. 2017 Oct 25. doi: 10.1097/SHK.0000000000001038. [Epub ahead of print] PMID: 29076972 [PubMed - as supplied by publisher] Similar articles

Malformed legacy source URL omitted; use the retained DOI or PubMed link

2018Human

Analytical interference of HBOC-201 (Hemopure, a synthetic hemoglobin-based oxygen carrier) on four common clinical chemistry platforms

Korte EA, Pozzi N, Wardrip N, Ayyoubi M, Jortani SA · Clinica Chimica Acta

Record details
Authors
Korte EA, Pozzi N, Wardrip N, Ayyoubi M, Jortani SA
Journal
Clinica Chimica Acta
Year
2018
Species / model
Human
Author institutions
Baptist Health Louisville, University of Louisville
Evidence type
Journal Article
DOI
10.1016/j.cca.2018.03.017
PMID
29580857
Original citation
Analytical interference of HBOC-201 (Hemopure, a synthetic hemoglobin-based oxygen carrier) on four common clinical chemistry platforms. Korte EA, Pozzi N, Wardrip N, Ayyoubi MT, Jortani SA. Clin Chim Acta. 2018 Jul;482:33-39. doi: 10.1016/j.cca.2018.03.017. Epub 2018 Mar 23. PMID: 29580857 [PubMed - indexed for MEDLINE] Similar articles
2018

Combined hypothermic and normothermic perfusion for the optimization of injured liver grafts

Quintini C, Lomaglio L, Pezzati D, Uso TD, Liu Q · Liver Transplantation

Record details
Authors
Quintini C, Lomaglio L, Pezzati D, Uso TD, Liu Q
Journal
Liver Transplantation
Year
2018
Author institutions
Cleveland Clinic, University of Pisa
Evidence type
Review / Editorial / Policy
DOI
10.1002/lt.25370
PMID
30371975
Original citation
Quintini C, Lomaglio L, Pezzati D, Uso TD, Liu Q. Combined Hypothermic and Normothermic Perfusion for the Optimization of Injured Liver Grafts. Liver Transplantation. 2018;24(12):1647-8.
2018

The effects of hemoglobin glutamer-200 and iNO on pulmonary vascular tone and arterial oxygenation in an experimental acute respiratory distress syndrome

Voelker MT, Bergmann A, Busch T, Jahn N, Laudi S, Noreikat K, Simon P, Bercker S · Pulm Pharmacol Ther

Record details
Authors
Voelker MT, Bergmann A, Busch T, Jahn N, Laudi S, Noreikat K, Simon P, Bercker S
Journal
Pulm Pharmacol Ther
Year
2018
Evidence type
Preclinical animal
DOI
10.1016/j.pupt.2018.01.009
PMID
29425776
Original citation
The effects of hemoglobin glutamer-200 and iNO on pulmonary vascular tone and arterial oxygenation in an experimental acute respiratory distress syndrome. Voelker MT, Bergmann A, Busch T, Jahn N, Laudi S, Noreikat K, Simon P, Bercker S. Pulm Pharmacol Ther. 2018 Apr;49:130-133. doi: 10.1016/j.pupt.2018.01.009. Epub 2018 Feb 6. PMID: 29425776 [PubMed - indexed for MEDLINE] Similar articles
2018Human

Use of the blood substitute HBOC-201 in critically ill patients during sickle crisis: a three-case series

Davis JM, El-Haj N, Shah NN, Schwartz G, Block M, Wall J, Tidswell M, Dinino E · Transfusion

Record details
Authors
Davis JM, El-Haj N, Shah NN, Schwartz G, Block M, Wall J, Tidswell M, Dinino E
Journal
Transfusion
Year
2018
Species / model
Human
Author institutions
Baystate Medical Center, Creighton University, Levine Cancer Institute, Louisville Veterinary Specialty and Emergency Services, Methodist Health System, Tufts University
Evidence type
Human clinical evidence
DOI
10.1111/trf.14386
PMID
29076161
Original citation
Use of the blood substitute HBOC-201 in critically ill patients during sickle crisis: a three-case series. Davis JM, El-Haj N, Shah NN, Schwartz G, Block M, Wall J, Tidswell M, DiNino E. Transfusion. 2018 Jan;58(1):132-137. doi: 10.1111/trf.14386. Epub 2017 Oct 26. PMID: 29076161 [PubMed - indexed for MEDLINE] Similar articles

Conflicting source title/year reconciled against the retained identified citation

2017

Bloodless reperfusion with the oxygen carrier HBOC-201 in acute myocardial infarction: a novel platform for cardioprotective probes delivery

García-Ruiz JM, Galán-Arriola C, Fernández-Jiménez R, Aguero J, Sánchez- González J, García-Alvarez A, Nuno-Ayala M, Dubé GP, Zafirelis Z, López-Martín GJ, Bernal JA, Lara-Pezzi E, Fuster V, Ibáñez B · Basic Res Cardiol

Record details
Authors
García-Ruiz JM, Galán-Arriola C, Fernández-Jiménez R, Aguero J, Sánchez- González J, García-Alvarez A, Nuno-Ayala M, Dubé GP, Zafirelis Z, López-Martín GJ, Bernal JA, Lara-Pezzi E, Fuster V, Ibáñez B
Journal
Basic Res Cardiol
Year
2017
Evidence type
Unclear - verify full text
DOI
10.1007/s00395-017-0605-6
PMID
28188434
Original citation
Bloodless reperfusion with the oxygen carrier HBOC-201 in acute myocardial infarction: a novel platform for cardioprotective probes delivery. García-Ruiz JM, Galán-Arriola C, Fernández-Jiménez R, Aguero J, Sánchez- González J, García-Alvarez A, Nuno-Ayala M, Dubé GP, Zafirelis Z, López-Martín GJ, Bernal JA, Lara-Pezzi E, Fuster V, Ibáñez B. Basic Res Cardiol. 2017 Mar;112(2):17. doi: 10.1007/s00395-017-0605-6. Epub 2017 Feb 10. PMID: 28188434 [PubMed - indexed for MEDLINE] Similar articles
2017Human

Hemoglobin-Based Oxygen Carrier Rescues Double-Transplant Patient From Life-Threatening Anemia

Gomez MF, Aljure O, Ciancio G, Lynn M · American Journal of Transplantation

Record details
Authors
Gomez MF, Aljure O, Ciancio G, Lynn M
Journal
American Journal of Transplantation
Year
2017
Species / model
Human
Author institutions
Jackson Memorial Hospital, University of Miami
Evidence type
Human clinical
DOI
10.1111/ajt.14226
PMID
28188676
Original citation
Hemoglobin-Based Oxygen Carrier Rescues Double-Transplant Patient From Life- Threatening Anemia. Gomez MF, Aljure O, Ciancio G, Lynn M. Am J Transplant. 2017 Jul;17(7):1941-1944. doi: 10.1111/ajt.14226. Epub 2017 Mar 17. PMID: 28188676 [PubMed - indexed for MEDLINE] Free Article Similar articles
2017Human

Management of life threatening post-partum hemorrhage with HBOC-201 in a Jehovah's witness

Mytinger A, Sheehan E, Blue N, Crookston K, Saeed A · Southwest Journal of Pulmonary and Critical Care

Record details
Authors
Mytinger A, Sheehan E, Blue N, Crookston K, Saeed A
Journal
Southwest Journal of Pulmonary and Critical Care
Year
2017
Species / model
Human
Author institutions
University of New Mexico
Evidence type
Human clinical evidence
DOI
10.13175/swjpcc031-17
Original citation
Mytinger A, Sheehan E, Blue N, Crookston K, Saeed A. Management of life threatening post-partum hemorrhage with HBOC-201 in a Jehovah’s witness. Southwest Journal of Pulmonary and Critical Care. 2017;14(4):177-84.

Citation and author information manually checked on the journal article page. Not represented as a PubMed-indexed record.

2017Porcine (Pig)

Normalization of hemoglobin-based oxygen carrier-201 induced vasoconstriction: targeting nitric oxide and endothelin

Taverne YJ, Wijs-Meijler DD, Hekkert MTL, Moon-Massat PF, Dubé GP, Duncker DJ, et al. · Journal of Applied Physiology

Record details
Authors
Taverne YJ, Wijs-Meijler DD, Hekkert MTL, Moon-Massat PF, Dubé GP, Duncker DJ, et al.
Journal
Journal of Applied Physiology
Year
2017
Species / model
Porcine (Pig)
Author institutions
Erasmus MC, Naval Medical Research Center, OPK Biotech
Evidence type
Journal Article
DOI
10.1152/japplphysiol.00677.2016
PMID
28183818
Original citation
Normalization of hemoglobin-based oxygen carrier-201 induced vasoconstriction: targeting nitric oxide and endothelin. Taverne YJ, de Wijs-Meijler D, Te Lintel Hekkert M, Moon-Massat PF, Dubé GP, Duncker DJ, Merkus D. J Appl Physiol (1985). 2017 May 1;122(5):1227-1237. doi: 10.1152/japplphysiol.00677.2016. Epub 2017 Feb 9. PMID: 28183818 [PubMed - indexed for MEDLINE] Free Article Similar articles
2017

Storage of nitroglycerin (NTG) admixed with HBOC-201 for 30 days in polyolefin plastic bags: a pilot study

Nigam S, McCarron R, Arnaud F · Drug Delivery and Translational Research

Record details
Authors
Nigam S, McCarron R, Arnaud F
Journal
Drug Delivery and Translational Research
Year
2017
Author institutions
Naval Medical Research Center, U.S. Army Medical Research and Materiel Command, Uniformed Services University
Evidence type
Journal Article
DOI
10.1007/s13346-017-0411-6
PMID
28744782
Original citation
Storage of nitroglycerin (NTG) admixed with HBOC-201 for 30 days in polyolefin plastic bags: a pilot study. Nigam S, McCarron R, Arnaud F. Drug Deliv Transl Res. 2017 Oct;7(5):674-682. doi: 10.1007/s13346-017-0411-6. PMID: 28744782 [PubMed - indexed for MEDLINE] Similar articles
2017

Use of a hemoglobin substitute (HBOC-201) to treat acute anemia in a leukemic patient with anti-Vel antibodies

Ayyoubi MT, Manapuram S, Hashmi H, McDaniel K, Basu SK, Tse W, Krem MM · Blood

Summary & details

Conference abstract reporting the use of HBOC-201 for acute anemia in a patient with leukemia and anti-Vel antibodies. Published in Blood, volume 130, supplement 1, page 4928 (2017).

Authors
Ayyoubi MT, Manapuram S, Hashmi H, McDaniel K, Basu SK, Tse W, Krem MM
Journal
Blood
Year
2017
Evidence type
Human clinical evidence
Original citation
Ayyoubi MT, Manapuram S, Hashmi H, McDaniel K, Basu SK, Tse W, Krem MM. Use of a hemoglobin substitute (HBOC-201) to treat acute anemia in a leukemic patient with anti-Vel antibodies. Blood. 2017 Dec 8;130:4928.

The article title, authors, year and abstract were verified on the publisher’s ScienceDirect page on 11 October 2026.

2017

Use of hemoglobin based oxygen carrier HBOC-021 (Hemopure) as a bridge during emergencies in patients unable to receive blood products: experience at a tertiary care center

Bari S, Rabinovich M, Curry M, et al · Blood

Summary & details

Conference abstract on the use of a hemoglobin-based oxygen carrier as a bridge during emergencies for patients unable to receive blood products. Published in Blood, volume 130, supplement 1, page 4926 (2017).

Authors
Bari S, Rabinovich M, Curry M, et al
Journal
Blood
Year
2017
Evidence type
Human clinical
Original citation
Bari S, Rabinovich M, Curry M, et al. Use of hemoglobin based oxygen carrier HBOC-021 (Hemopure) as a bridge during emergencies in patients unable to receive blood products: experience at a tertiary care center. Blood. 2017;130(Suppl 1):4926

Publisher-indexed title, year, journal and page match the supplied citation. The legacy ASH destination has been replaced by the corresponding ScienceDirect article page.

2016Human

Difficult to swallow: warm autoimmune hemolytic anemia in a Jehovah's Witness treated with hemoglobin concentrate complicated by achalasia

Epperla N, Strouse C, Vansandt AM, Foy P · Transfusion

Record details
Authors
Epperla N, Strouse C, Vansandt AM, Foy P
Journal
Transfusion
Year
2016
Species / model
Human
Author institutions
Medical College of Wisconsin, Oregon Health and Science University
Evidence type
Human clinical evidence
DOI
10.1111/trf.13607
PMID
27062564
Original citation
Difficult to swallow: warm autoimmune hemolytic anemia in a Jehovah's Witness treated with hemoglobin concentrate complicated by achalasia. Epperla N, Strouse C, VanSandt AM, Foy P. Transfusion. 2016 Jul;56(7):1801-6. doi: 10.1111/trf.13607. Epub 2016 Apr 6. PMID: 27062564 [PubMed - indexed for MEDLINE] Similar articles
2016

Fetal oxygen content is restored with Oxyglobin resuscitation after maternal hemorrhage

Moon PF, Bliss SP, Posner LP, Erb HN, Nathanielsz PW · Veterinary Anaesthesia and Analgesia

Record details
Authors
Moon PF, Bliss SP, Posner LP, Erb HN, Nathanielsz PW
Journal
Veterinary Anaesthesia and Analgesia
Year
2016
Evidence type
Veterinary clinical / research
DOI
10.1046/j.1467-2987.2001.temp.doc.x-i10
PMID
28404333
Original citation
Moon PF, Bliss SP, Posner LP, Erb HN, Nathanielsz PW. Fetal oxygen content is restored with Oxyglobin resuscitation after maternal hemorrhage. Vet Anaesth Analg. 2001 Apr;28(2):104-105. doi: 10.1046/j.1467-2987.2001.temp.doc.x-i10. Epub 2016 Nov 15. No abstract available. PMID:28404333
2016Human

Hemoglobin glutamer-250 (bovine) in South Africa: consensus usage guidelines from clinician experts who have treated patients

Mer M, Hodgson E, Wallis L, Jacobson B, Levien L, Snyman J, Sussman MJ, James M, van Gelder A, Allgaier R, Jahr JS · Transfusion

Record details
Authors
Mer M, Hodgson E, Wallis L, Jacobson B, Levien L, Snyman J, Sussman MJ, James M, van Gelder A, Allgaier R, Jahr JS
Journal
Transfusion
Year
2016
Species / model
Human
Author institutions
Charlotte Maxeke Johannesburg Academic Hospital, Groote Schuur Hospital, Milpark Hospital, National Health Laboratory Service, Nkosi Albert Luthuli Hospital, Stellenbosch University, Steve Biko Academic Hospital, Sunninghill Hospital, University of California, Los Angeles, University of Cape Town, University of Pretoria, University of the Witwatersrand
Evidence type
Reviews, clinical context & policy
DOI
10.1111/trf.13726
PMID
27658499
Original citation
Hemoglobin glutamer-250 (bovine) in South Africa: consensus usage guidelines from clinician experts who have treated patients. Mer M, Hodgson E, Wallis L, Jacobson B, Levien L, Snyman J, Sussman MJ, James M, van Gelder A, Allgaier R, Jahr JS. Transfusion. 2016 Oct;56(10):2631-2636. doi: 10.1111/trf.13726. Epub 2016 Sep 23. PMID: 27658499 [PubMed - indexed for MEDLINE] Similar articles
2016

Plasma colloid osmotic pressure after blood volume repletion with Oxyglobin, hetastarch, or whole blood in pregnant sheep

Posner LP, Moon PF, Bliss SP, Gleed RD, Erb HN · Veterinary Anaesthesia and Analgesia

Record details
Authors
Posner LP, Moon PF, Bliss SP, Gleed RD, Erb HN
Journal
Veterinary Anaesthesia and Analgesia
Year
2016
Evidence type
Veterinary clinical / research
PMID
28404331
Original citation
Plasma colloid osmotic pressure after blood volume repletion with Oxyglobin, hetastarch, or whole blood in pregnant sheep. Posner LP, Moon PF, Bliss SP, Gleed RD, Erb HN. Vet Anaesth Analg. 2001 Apr;28(2):104. doi: 10.1046/j.1467- 2987.2001.temp.doc.x-i9. Epub 2016 Nov 15. No abstract available. PMID: 28404331 [PubMed] Similar articles

Truncated DOI omitted from links

2015Other animal

A successful transfusion in a tamandua (Tamandua tetradactyla) using both whole blood and blood replacement products

Raines JA, Storms T · Journal of Zoo and Wildlife Medicine

Record details
Authors
Raines JA, Storms T
Journal
Journal of Zoo and Wildlife Medicine
Year
2015
Species / model
Other animal
Evidence type
Journal Article; Case Reports
DOI
10.1638/2014-0093r.1
PMID
25831593
Original citation
A successful transfusion in a tamandua (Tamandua tetradactyla) using both whole blood and blood replacement products. Raines JA, Storms T. J Zoo Wildl Med. 2015 Mar;46(1):161-3. PMID: 25831593 [PubMed - indexed for MEDLINE] Similar articles
2015Porcine (Pig)

A whole blood-based perfusate provides superior preservation of myocardial function during ex vivo heart perfusion

White CW, Hasanally D, Mundt P, Li Y, Xiang B, Klein J, Müller A, Ambrose E, Ravandi A, Arora RC, Lee TW, Hryshko LV, Large S, Tian G, Freed DH · Journal of Heart and Lung Transplantation

Record details
Authors
White CW, Hasanally D, Mundt P, Li Y, Xiang B, Klein J, Müller A, Ambrose E, Ravandi A, Arora RC, Lee TW, Hryshko LV, Large S, Tian G, Freed DH
Journal
Journal of Heart and Lung Transplantation
Year
2015
Species / model
Porcine (Pig)
Author institutions
National Research Council Institute for Biodiagnostics, Papworth Hospital, St. Boniface Hospital, University of Alberta, University of Manitoba
Evidence type
In vitro / analytical
DOI
10.1016/j.healun.2014.09.021
PMID
25447577
Original citation
White CW, Hasanally D2, Mundt P, Li Y, Xiang B, Klein J, Müller A, Ambrose E, Ravandi A, Arora RC, Lee TW, Hryshko LV, Large S, Tian G, Freed DH. A whole blood-based perfusate provides superior preservation of myocardial function during ex vivo heart perfusion. J Heart Lung Transplant. 2015 Jan;34(1):113-21. doi: 10.1016/j.healun.2014.09.021. Epub 2014 Sep 28.
2015Canine (Dog)

Absence of developmental toxicity in a canine model after infusion of a hemoglobin-based oxygen carrier: Implications for risk assessment

Holson JF, Stump DG, Pearce LB, Watson RE, DeSesso JM · Reproductive Toxicology

Record details
Authors
Holson JF, Stump DG, Pearce LB, Watson RE, DeSesso JM
Journal
Reproductive Toxicology
Year
2015
Species / model
Canine (Dog)
Author institutions
Biologics Consulting Group, Exponent, Georgetown University, SNBL USA, WIL Research Laboratories
Evidence type
Journal Article
DOI
10.1016/j.reprotox.2015.01.006
PMID
25697570
Original citation
Absence of developmental toxicity in a canine model after infusion of a hemoglobin-based oxygen carrier: Implications for risk assessment. Holson JF, Stump DG, Pearce LB, Watson RE, DeSesso JM. Reprod Toxicol. 2015 Apr;52:101-7. doi: 10.1016/j.reprotox.2015.01.006. Epub 2015 Feb 16. PMID: 25697570 [PubMed - indexed for MEDLINE] Similar articles
2014Human

A safety and efficacy evaluation of hemoglobin-based oxygen carrier HBOC-201 in a randomized, multicenter red blood cell controlled trial in noncardiac surgery patients

Van Hemelrijck J, Levien LJ, Veeckman L, Pitman A, Zafirelis Z, Standl T · Anesthesia & Analgesia

Record details
Authors
Van Hemelrijck J, Levien LJ, Veeckman L, Pitman A, Zafirelis Z, Standl T
Journal
Anesthesia & Analgesia
Year
2014
Species / model
Human
Author institutions
KU Leuven University Hospitals, Milpark Hospital, University Medical Center Hamburg-Eppendorf
Evidence type
Human clinical evidence
DOI
10.1213/ane.0000000000000305
PMID
24977631
Original citation
A safety and efficacy evaluation of hemoglobin-based oxygen carrier HBOC-201 in a randomized, multicenter red blood cell controlled trial in noncardiac surgery patients. Van Hemelrijck J, Levien LJ, Veeckman L, Pitman A, Zafirelis Z, Standl T. Anesth Analg. 2014 Oct;119(4):766-76. doi: 10.1213/ANE.0000000000000305. PMID: 24977631 [PubMed - indexed for MEDLINE] Similar articles
2014Rodent

Effects of a hemoglobin-based oxygen carrier (HBOC-201) and derivatives with altered oxygen affinity and viscosity on systemic and microcirculatory variables in a top-load rat model

Song BK, Nugent WH, Moon-Massat PF, Pittman RN · Microvascular Research

Record details
Authors
Song BK, Nugent WH, Moon-Massat PF, Pittman RN
Journal
Microvascular Research
Year
2014
Species / model
Rodent
Author institutions
Naval Medical Research Center, Virginia Commonwealth University
Evidence type
Comparative Study; Research Support, Non-U.S. Gov't; research-article; Journal Article; Research Support, N.I.H., Extramural
DOI
10.1016/j.mvr.2014.07.005
PMID
25046829
Original citation
Effects of a hemoglobin-based oxygen carrier (HBOC-201) and derivatives with altered oxygen affinity and viscosity on systemic and microcirculatory variables in a top-load rat model. Song BK, Nugent WH, Moon-Massat PF, Pittman RN. Microvasc Res. 2014 Sep;95:124-30. doi: 10.1016/j.mvr.2014.07.005. Epub 2014 Jul 18. PMID: 25046829 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2014Human

Experience with the use of Hemopure in the care of a massively burned adult

Lundy JB, Lewis CJ, Cancio LC, Cap AP · International Journal of Burns and Trauma

Record details
Authors
Lundy JB, Lewis CJ, Cancio LC, Cap AP
Journal
International Journal of Burns and Trauma
Year
2014
Species / model
Human
Author institutions
U.S. Army Institute of Surgical Research
Evidence type
Human clinical evidence
PMID
24624314
Original citation
Experience with the use of Hemopure in the care of a massively burned adult. Lundy JB, Lewis CJ, Cancio LC, Cap AP. Int J Burns Trauma. 2014 Feb 22;4(1):45-8. eCollection 2014. PMID: 24624314 [PubMed] Free PMC Article Similar articles
2014Porcine (Pig) · Human

Hypertonic HBOC-201 decreases neutrophil activation after hemorrhagic shock

Rivera-Chávez FA, Lu A, Liu MM, Abdalla A, Minei JP · Journal of Investigative Surgery

Record details
Authors
Rivera-Chávez FA, Lu A, Liu MM, Abdalla A, Minei JP
Journal
Journal of Investigative Surgery
Year
2014
Species / model
Porcine (Pig), Human
Author institutions
University of Texas Southwestern Medical Center
Evidence type
Preclinical evidence supporting human development
DOI
10.3109/08941939.2013.826756
PMID
24456255
Original citation
Hypertonic HBOC-201 decreases neutrophil activation after hemorrhagic shock. Rivera-Chávez FA, Lu A, Liu MM, Abdalla A, Minei JP. J Invest Surg. 2014 Feb;27(1):14-20. doi: 10.3109/08941939.2013.826756. PMID: 24456255 [PubMed - indexed for MEDLINE] Similar articles
2014Rodent

Resuscitation from hemorrhagic shock using polymerized hemoglobin compared to blood

Ortiz D, Barros M, Yan S, Cabrales P · Am J Emerg Med

Record details
Authors
Ortiz D, Barros M, Yan S, Cabrales P
Journal
Am J Emerg Med
Year
2014
Species / model
Rodent
Author institutions
University of California, San Diego
Evidence type
Preclinical evidence supporting human development
DOI
10.1016/j.ajem.2013.11.045
PMID
24418449
Original citation
Resuscitation from hemorrhagic shock using polymerized hemoglobin compared to blood. Ortiz D, Barros M, Yan S, Cabrales P. Am J Emerg Med. 2014 Mar;32(3):248-55. doi: 10.1016/j.ajem.2013.11.045. Epub 2013 Dec 7. PMID: 24418449 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2013Rodent

Effects of N-Acetyl-L-Cysteine and Hyaluronic Acid on HBOC-201-Induced Systemic and Cerebral Vasoconstriction in the Rat

Abutarboush R, Scultetus A, Pappas G, Arnaud F, Auker C, McCarron R, Moon-Massat PF · Current Drug Discovery Technologies

Record details
Authors
Abutarboush R, Scultetus A, Pappas G, Arnaud F, Auker C, McCarron R, Moon-Massat PF
Journal
Current Drug Discovery Technologies
Year
2013
Species / model
Rodent
Author institutions
Naval Medical Research Center
Evidence type
Research Support, U.S. Gov't, Non-P.H.S.; Journal Article
DOI
10.2174/15701638113109990034
PMID
24074305
Original citation
Effects of N-acetyl-L-cysteine and hyaluronic acid on HBOC-201-induced systemic and cerebral vasoconstriction in the rat. Abutarboush R, Scultetus A, Pappas G, Arnaud F, Auker C, McCarron R, Moon- Massat PF. Curr Drug Discov Technol. 2013 Dec;10(4):315-24. PMID: 24074305 [PubMed - indexed for MEDLINE] Similar articles
2012Porcine (Pig)

Pre-hospital Resuscitation with HBOC-201 and rFVIIa Compared to HBOC-201 Alone in Uncontrolled Hemorrhagic Shock in Swine

Haque A, Arnaud F, Teranishi K, Okada T, Kim B, Moon-Massat PF, Auker C, McCarron R, Freilich D, Scultetus AH · Artificial Cells, Blood Substitutes, and Biotechnology

Record details
Authors
Haque A, Arnaud F, Teranishi K, Okada T, Kim B, Moon-Massat PF, Auker C, McCarron R, Freilich D, Scultetus AH
Journal
Artificial Cells, Blood Substitutes, and Biotechnology
Year
2012
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.3109/10731199.2011.585615
PMID
21806503
Original citation
Pre-hospital resuscitation with HBOC-201 and rFVIIa compared to HBOC-201 alone in uncontrolled hemorrhagic shock in swine. Haque A, Arnaud F, Teranishi K, Okada T, Kim B, Moon-Massat PF, Auker C, McCarron R, Freilich D, Scultetus AH. Artif Cells Blood Substit Immobil Biotechnol. 2012 Feb;40(1-2):44-55. doi: 10.3109/10731199.2011.585615. Epub 2011 Aug 2. PMID: 21806503 [PubMed - indexed for MEDLINE] Similar articles
2012Porcine (Pig)

Sodium nitroprusside ameliorates systemic but not pulmonary HBOC-201-induced vasoconstriction: An exploratory study in a swine controlled haemorrhage model

Arnaud F, Scultetus AH, Haque A, Saha B, Kim B, Auker C, Moon-Massat P, McCarron R, Freilich D · Resuscitation

Record details
Authors
Arnaud F, Scultetus AH, Haque A, Saha B, Kim B, Auker C, Moon-Massat P, McCarron R, Freilich D
Journal
Resuscitation
Year
2012
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1016/j.resuscitation.2012.01.018
PMID
22286048
Original citation
Sodium nitroprusside ameliorates systemic but not pulmonary HBOC-201-induced vasoconstriction: an exploratory study in a swine controlled haemorrhage model. Arnaud F, Scultetus AH, Haque A, Saha B, Kim B, Auker C, Moon-Massat P, McCarron R, Freilich D. Resuscitation. 2012 Aug;83(8):1038-45. doi: 10.1016/j.resuscitation.2012.01.018. Epub 2012 Jan 28. PMID: 22286048 [PubMed - indexed for MEDLINE] Similar articles
2012Porcine (Pig)

The effect HBOC-201 and sodium nitrite resuscitation after uncontrolled haemorrhagic shock in swine

Moon-Massat P, Scultetus A, Arnaud F, Brown A, Haque A, Saha B, Kim B, Sagini E, McGwin G Jr, Auker C, McCarron R, Freilich D · Injury

Record details
Authors
Moon-Massat P, Scultetus A, Arnaud F, Brown A, Haque A, Saha B, Kim B, Sagini E, McGwin G Jr, Auker C, McCarron R, Freilich D
Journal
Injury
Year
2012
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1016/j.injury.2010.10.013
PMID
21094491
Original citation
The effect HBOC-201 and sodium nitrite resuscitation after uncontrolled haemorrhagic shock in swine. Moon-Massat P, Scultetus A, Arnaud F, Brown A, Haque A, Saha B, Kim B, Sagini E, McGwin G Jr, Auker C, McCarron R, Freilich D. Injury. 2012 May;43(5):638-47. doi: 10.1016/j.injury.2010.10.013. Epub 2010 Nov 20. PMID: 21094491 [PubMed - indexed for MEDLINE] Similar articles
2011Feline (Cat)

Evaluation of the effects of bovine hemoglobin glutamer-200 on systolic arterial blood pressure in hypotensive cats: 44 cases (1997-2008)

Wehausen CE, Kirby R, Rudloff E · Journal of the American Veterinary Medical Association

Record details
Authors
Wehausen CE, Kirby R, Rudloff E
Journal
Journal of the American Veterinary Medical Association
Year
2011
Species / model
Feline (Cat)
Author institutions
Animal Emergency Clinic, Oakdale
Evidence type
Journal Article
DOI
10.2460/javma.238.7.909
PMID
21453180
Original citation
Evaluation of the effects of bovine hemoglobin glutamer-200 on systolic arterial blood pressure in hypotensive cats: 44 cases (1997-2008). Wehausen CE, Kirby R, Rudloff E. J Am Vet Med Assoc. 2011 Apr 1;238(7):909-14. doi: 10.2460/javma.238.7.909. PMID: 21453180 [PubMed - indexed for MEDLINE] Similar articles

Metadata corrected 16 September 2026: the prior journal label 'Hb-200' was erroneous. PubMed identifies Journal of the American Veterinary Medical Association, 2011;238(7):909-914, DOI 10.2460/javma.238.7.909.

2011Human

Is There a Role for Hemopure in the Prehospital Setting?

Minei JP · Journal of Trauma

Record details
Authors
Minei JP
Journal
Journal of Trauma
Year
2011
Species / model
Human
Author institutions
University of Texas Southwestern Medical Center
Evidence type
Human clinical evidence; Reviews, clinical context & policy
DOI
10.1097/ta.0b013e31821a5a09
PMID
21841569
Original citation
Minei JP. Is There a Role for Hemopure in the Prehospital Setting? The Journal of Trauma: Injury, Infection, and Critical Care. 2011;70.
2011

Vital organ tissue oxygenation after serial normovolemic exchange transfusion with HBOC-201 in anesthetized swine

Muir WW, Ilangovan G, Zweier JL, Moon-Massat PF, Rentko VT · Shock

Record details
Authors
Muir WW, Ilangovan G, Zweier JL, Moon-Massat PF, Rentko VT
Journal
Shock
Year
2011
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/shk.0b013e31821366f6
PMID
21330945
Original citation
Vital organ tissue oxygenation after serial normovolemic exchange transfusion with HBOC-201 in anesthetized swine. Muir WW, Ilangovan G, Zweier JL, Moon-Massat PF, Rentko VT. Shock. 2011 Jun;35(6):597-603. doi: 10.1097/SHK.0b013e31821366f6. PMID: 21330945 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2010

Amylase and lipase detection in hemorrhaged animals treated with HBOC-201

Arnaud F, McCarron R, Freilich D · Artificial Cells, Blood Substitutes, and Biotechnology

Record details
Authors
Arnaud F, McCarron R, Freilich D
Journal
Artificial Cells, Blood Substitutes, and Biotechnology
Year
2010
Evidence type
Preclinical evidence supporting human development
DOI
10.3109/10731199.2010.516260
PMID
21171938
Original citation
Amylase and lipase detection in hemorrhaged animals treated with HBOC-201. Arnaud F, McCarron R, Freilich D. Artif Cells Blood Substit Immobil Biotechnol. 2011 Jun;39(3):155-61. doi: 10.3109/10731199.2010.516260. Epub 2010 Dec 21. PMID: 21171938 [PubMed - indexed for MEDLINE] Similar articles
2010

Does HBOC-201 (Hemopure) affect platelet function in orthopedic surgery: a single-site analysis from a multicenter study

Jahr JS, Liu H, Albert OK, Gull A, Moallempour M, Lim J, Gosselin R · American Journal of Therapeutics

Record details
Authors
Jahr JS, Liu H, Albert OK, Gull A, Moallempour M, Lim J, Gosselin R
Journal
American Journal of Therapeutics
Year
2010
Evidence type
Pending full-text classification
DOI
10.1097/mjt.0b013e3181a2b08d
PMID
19417588
Original citation
Does HBOC-201 (Hemopure) affect platelet function in orthopedic surgery: a single-site analysis from a multicenter study. Jahr JS, Liu H, Albert OK, Gull A, Moallempour M, Lim J, Gosselin R. Am J Ther. 2010 Mar-Apr;17(2):140-7. doi: 10.1097/MJT.0b013e3181a2b08d. PMID: 19417588 [PubMed - indexed for MEDLINE] Similar articles
2010

Dose response of sodium nitrite on vasoactivity associated with HBOC-201 in a swine model of controlled hemorrhage

Arnaud F, Scultetus AH, Kim B, Haque A, Saha B, Nigam S, Moon-Massat P, Auker C, McCarron R, Freilich D · Artificial Cells, Blood Substitutes, and Biotechnology

Record details
Authors
Arnaud F, Scultetus AH, Kim B, Haque A, Saha B, Nigam S, Moon-Massat P, Auker C, McCarron R, Freilich D
Journal
Artificial Cells, Blood Substitutes, and Biotechnology
Year
2010
Evidence type
Preclinical evidence supporting human development
DOI
10.3109/10731199.2010.533126
PMID
21133651
Original citation
Dose response of sodium nitrite on vasoactivity associated with HBOC-201 in a swine model of controlled hemorrhage. Arnaud F, Scultetus AH, Kim B, Haque A, Saha B, Nigam S, Moon-Massat P, Auker C, McCarron R, Freilich D. Artif Cells Blood Substit Immobil Biotechnol. 2011 Aug;39(4):195-205. doi: 10.3109/10731199.2010.533126. Epub 2010 Dec 6. PMID: 21133651 [PubMed - indexed for MEDLINE] Similar articles
2010

Hemoglobin-based oxygen carrier (HBOC-201) and escalating doses of recombinant factor VIIa (rFVIIa) as a novel pre-hospital resuscitation fluid in a swine model of severe uncontrolled hemorrhage

Scultetus A, Arnaud F, Kaplan L, Shander A, Philbin N, Rice J, McCarron R, Freilich D · Artificial Cells, Blood Substitutes, and Biotechnology

Record details
Authors
Scultetus A, Arnaud F, Kaplan L, Shander A, Philbin N, Rice J, McCarron R, Freilich D
Journal
Artificial Cells, Blood Substitutes, and Biotechnology
Year
2010
Evidence type
Preclinical evidence supporting human development
DOI
10.3109/10731199.2010.501755
PMID
20645681
Original citation
Hemoglobin-based oxygen carrier (HBOC-201) and escalating doses of recombinant factor VIIa (rFVIIa) as a novel pre-hospital resuscitation fluid in a swine model of severe uncontrolled hemorrhage. Scultetus A, Arnaud F, Kaplan L, Shander A, Philbin N, Rice J, McCarron R, Freilich D. Artif Cells Blood Substit Immobil Biotechnol. 2011 Apr;39(2):59-68. doi: 10.3109/10731199.2010.501755. Epub 2010 Jul 20. PMID: 20645681 [PubMed - indexed for MEDLINE] Similar articles

Malformed legacy source URL omitted; use the retained DOI or PubMed link

2010

Nitroglycerin attenuates vasoconstriction of HBOC-201 during hemorrhagic shock resuscitation

Katz LM, Manning JE, McCurdy S, Sproule C, McGwin G Jr, Moon-Massat P, Cairns CB, Freilich D · Resuscitation

Record details
Authors
Katz LM, Manning JE, McCurdy S, Sproule C, McGwin G Jr, Moon-Massat P, Cairns CB, Freilich D
Journal
Resuscitation
Year
2010
Evidence type
Pending full-text classification
DOI
10.1016/j.resuscitation.2009.12.015
PMID
20080328
Original citation
Nitroglycerin attenuates vasoconstriction of HBOC-201 during hemorrhagic shock resuscitation. Katz LM, Manning JE, McCurdy S, Sproule C, McGwin G Jr, Moon-Massat P, Cairns CB, Freilich D. Resuscitation. 2010 Apr;81(4):481-7. doi: 10.1016/j.resuscitation.2009.12.015. Epub 2010 Jan 18. PMID: 20080328 [PubMed - indexed for MEDLINE] Similar articles
2010Porcine (Pig)

Preoxygenated hemoglobin-based oxygen carrier HBOC-201 annihilates myocardial ischemia during brief coronary artery occlusion in pigs

Hekkert MTL, Dubé GP, Regar E, Boer MD, Vranckx P, Giessen WJVD, et al. · American Journal of Physiology

Record details
Authors
Hekkert MTL, Dubé GP, Regar E, Boer MD, Vranckx P, Giessen WJVD, et al.
Journal
American Journal of Physiology
Year
2010
Species / model
Porcine (Pig)
Author institutions
Erasmus MC
Evidence type
Preclinical animal
DOI
10.1152/ajpheart.00667.2009
PMID
20061545
Original citation
Preoxygenated hemoglobin-based oxygen carrier HBOC-201 annihilates myocardial ischemia during brief coronary artery occlusion in pigs. Te Lintel Hekkert M, Dubé GP, Regar E, de Boer M, Vranckx P, van der Giessen WJ, Serruys PW, Duncker DJ. Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H1103-13. doi: 10.1152/ajpheart.00667.2009. Epub 2010 Jan 8. PMID: 20061545 [PubMed - indexed for MEDLINE] Free Article Similar articles
2010Feline (Cat)

Primary Immune-Mediated Thrombocytopenia in Cats

Wondratschek C, Weingart C, Kohn B · Journal of the American Animal Hospital Association

Record details
Authors
Wondratschek C, Weingart C, Kohn B
Journal
Journal of the American Animal Hospital Association
Year
2010
Species / model
Feline (Cat)
Author institutions
Free University of Berlin
Evidence type
Journal Article
DOI
10.5326/0460012
PMID
20045832
Original citation
Primary immune-mediated thrombocytopenia in cats. Wondratschek C, Weingart C, Kohn B. J Am Anim Hosp Assoc. 2010 Jan-Feb;46(1):12-9. PMID: 20045832 [PubMed - indexed for MEDLINE] Similar articles
2009Canine (Dog)

A prospective, randomized comparison of Oxyglobin (HB-200) and packed red blood cell transfusion for canine babesiosis

Zambelli AB, Leisewitz AL · Journal of Veterinary Emergency and Critical Care

Record details
Authors
Zambelli AB, Leisewitz AL
Journal
Journal of Veterinary Emergency and Critical Care
Year
2009
Species / model
Canine (Dog)
Author institutions
University of Pretoria
Evidence type
Journal Article
DOI
10.1111/j.1476-4431.2009.00386.x
PMID
19691591
Original citation
A prospective, randomized comparison of Oxyglobin (HB-200) and packed red blood cell transfusion for canine babesiosis. Zambelli AB, Leisewitz AL. J Vet Emerg Crit Care (San Antonio). 2009 Feb;19(1):102-12. doi: 10.1111/j.1476- 4431.2009.00386.x. PMID: 19691591 [PubMed - indexed for MEDLINE] Similar articles

Prospective randomized clinical comparison of Oxyglobin with packed red blood cell transfusion in 12 naturally infected dogs. PubMed PMID 19691591.

2009Avian (Bird)

Avian Transfusion Medicine

Shaw S, Tully T, Nevarez J · Compend Contin Educ Vet

Record details
Authors
Shaw S, Tully T, Nevarez J
Journal
Compend Contin Educ Vet
Year
2009
Species / model
Avian (Bird)
Author institutions
Oklahoma City Zoo
Evidence type
Reviews, clinical context & policy
PMID
20180223
Original citation
Avian transfusion medicine. Shaw S, Tully T, Nevarez J. Compend Contin Educ Vet. 2009 Dec;31(12):E1-7; quiz E7. Review. PMID: 20180223 [PubMed - indexed for MEDLINE] Similar articles
2009Avian (Bird)

Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos)

Lichtenberger M, Orcutt C, Cray C, Thamm DH, DeBehnke D, Page C, Mull L, Kirby R · Journal of Veterinary Emergency and Critical Care

Record details
Authors
Lichtenberger M, Orcutt C, Cray C, Thamm DH, DeBehnke D, Page C, Mull L, Kirby R
Journal
Journal of Veterinary Emergency and Critical Care
Year
2009
Species / model
Avian (Bird)
Author institutions
Milwaukee Emergency Clinic for Animals and Referral Services
Evidence type
Randomized Controlled Trial; Journal Article
DOI
10.1111/j.1476-4431.2009.00465.x
PMID
19821888
Original citation
Lichtenberger M, Orcutt C, Cray C, Thamm DH, DeBehnke D, Page C, et al. Comparison of fluid types for resuscitation after acute blood loss in mallard ducks (Anas platyrhynchos). J Vet Emerg Crit Care (San Antonio). 2009 Oct;19(5):467-72. doi: 10.1111/j.1476-4431.2009.00465.x. PMID:19821888
2009Rodent

Effects of hemodilution with a hemoglobin-based oxygen carrier (HBOC-201) on ischemia/reperfusion injury in a model of partial warm liver ischemia of the rat

Zapletal C, Bode A, Lorenz MW, Gebhard M-M, Golling M · Microvascular Research

Record details
Authors
Zapletal C, Bode A, Lorenz MW, Gebhard M-M, Golling M
Journal
Microvascular Research
Year
2009
Species / model
Rodent
Author institutions
Goethe University Frankfurt
Evidence type
In vitro / analytical
DOI
10.1016/j.mvr.2009.08.005
PMID
19715706
Original citation
Effects of hemodilution with a hemoglobin-based oxygen carrier (HBOC-201) on ischemia/reperfusion injury in a model of partial warm liver ischemia of the rat. Zapletal C, Bode A, Lorenz MW, Gebhard MM, Golling M. Microvasc Res. 2009 Dec;78(3):386-92. doi: 10.1016/j.mvr.2009.08.005. Epub 2009 Aug 26. PMID: 19715706 [PubMed - indexed for MEDLINE] Similar articles
2009Rodent · Human

Endothelin-1 contributes to hemoglobin glutamer-200-mediated hepatocellular dysfunction after hemorrhagic shock

Kubulus D, Mathes A, Reus E, Pradarutti S, Pavlidis D, Thierbach JT, Heiser J, Wolf B, Bauer I, Rensing H · Shock

Record details
Authors
Kubulus D, Mathes A, Reus E, Pradarutti S, Pavlidis D, Thierbach JT, Heiser J, Wolf B, Bauer I, Rensing H
Journal
Shock
Year
2009
Species / model
Rodent, Human
Author institutions
Saarland University
Evidence type
Journal Article
DOI
10.1097/shk.0b013e318199352b
PMID
19106820
Original citation
Endothelin-1 contributes to hemoglobin glutamer-200-mediated hepatocellular dysfunction after hemorrhagic shock. Kubulus D, Mathes A, Reus E, Pradarutti S, Pavlidis D, Thierbach JT, Heiser J, Wolf B, Bauer I, Rensing H. Shock. 2009 Aug;32(2):179-89. doi: 10.1097/SHK.0b013e318199352b. PMID: 19106820 [PubMed - indexed for MEDLINE] Similar articles
2009Human

HBOC-201 use in traumatic brain injury: case report and review of literature

Marinaro J, Smith J, Tawil I, Billstrand M, Crookston KP · Transfusion

Record details
Authors
Marinaro J, Smith J, Tawil I, Billstrand M, Crookston KP
Journal
Transfusion
Year
2009
Species / model
Human
Author institutions
University of New Mexico
Evidence type
Reviews, clinical context & policy
DOI
10.1111/j.1537-2995.2009.02235.x
PMID
19497051
Original citation
HBOC-201 use in traumatic brain injury: case report and review of literature. Marinaro J, Smith J, Tawil I, Billstrand M, Crookston KP. Transfusion. 2009 Oct;49(10):2054-9. doi: 10.1111/j.1537-2995.2009.02235.x. Epub 2009 May 27. Review. PMID: 19497051 [PubMed - indexed for MEDLINE] Similar articles
2009Human

HBOC-201 Vasoactivity in a Phase III Clinical Trial in Orthopedic Surgery Subjects-Extrapolation of Potential Risk for Acute Trauma Trials

Freilich D, Pearce LB, Pitman A, Greenburg G, Berzins M, Bebris L, et al. · Journal of Trauma

Record details
Authors
Freilich D, Pearce LB, Pitman A, Greenburg G, Berzins M, Bebris L, et al.
Journal
Journal of Trauma
Year
2009
Species / model
Human
Author institutions
Naval Medical Research Center
Evidence type
Human clinical evidence
DOI
10.1097/ta.0b013e3181820d5c
PMID
19204509
Original citation
HBOC-201 vasoactivity in a phase III clinical trial in orthopedic surgery subjects-- extrapolation of potential risk for acute trauma trials. Freilich D, Pearce LB, Pitman A, Greenburg G, Berzins M, Bebris L, Ahlers S, McCarron R. J Trauma. 2009 Feb;66(2):365-76. doi: 10.1097/TA.0b013e3181820d5c. PMID: 19204509 [PubMed - indexed for MEDLINE] Similar articles
2009Human · In vitro / laboratory

Methemoglobin Effects on Coagulation: A Dose-Response Study With HBOC-200 (Oxyglobin) in a Thrombelastogram Model

Moallempour M, Jahr JS, Lim JC, Weeks D, Butch A, Driessen B · Journal of Cardiothoracic and Vascular Anesthesia

Record details
Authors
Moallempour M, Jahr JS, Lim JC, Weeks D, Butch A, Driessen B
Journal
Journal of Cardiothoracic and Vascular Anesthesia
Year
2009
Species / model
Human, In vitro / laboratory
Author institutions
University of California, Los Angeles
Evidence type
Comparative Study; Journal Article
DOI
10.1053/j.jvca.2008.06.006
PMID
18834828
Original citation
Methemoglobin effects on coagulation: a dose-response study with HBOC-200 (Oxyglobin) in a thrombelastogram model. Moallempour M, Jahr JS, Lim JC, Weeks D, Butch A, Driessen B. J Cardiothorac Vasc Anesth. 2009 Feb;23(1):41-7. doi: 10.1053/j.jvca.2008.06.006. Epub 2008 Aug 29. PMID: 18834828 [PubMed - indexed for MEDLINE] Similar articles
2009Rodent

Polymerized Bovine Hemoglobin Can Improve Small-Volume Resuscitation from Hemorrhagic Shock in Hamsters

Cabrales P, Tsai AG, Intaglietta M · Shock

Record details
Authors
Cabrales P, Tsai AG, Intaglietta M
Journal
Shock
Year
2009
Species / model
Rodent
Author institutions
La Jolla Bioengineering Institute, University of California, San Diego
Evidence type
Journal Article; Research Support, N.I.H., Extramural
DOI
10.1097/shk.0b013e318180ff63
PMID
18636045
Original citation
Cabrales P, Tsai AG, Intaglietta M. Polymerized Bovine Hemoglobin Can Improve Small-Volume Resuscitation From Hemorrhagic Shock In Hamsters. Shock. 2009;31(3):300–7.
2009

Prevention of the pulmonary vasoconstrictor effects of HBOC-201 in awake lambs by continuously breathing nitric oxide

Yu B, Volpato GP, Chang K, Bloch KD, Zapol WM · Anesthesiology

Record details
Authors
Yu B, Volpato GP, Chang K, Bloch KD, Zapol WM
Journal
Anesthesiology
Year
2009
Evidence type
Unclear — verify full text
DOI
10.1097/aln.0b013e318190bc4f
PMID
19104178
Original citation
Prevention of the pulmonary vasoconstrictor effects of HBOC-201 in awake lambs by continuously breathing nitric oxide. Yu B, Volpato GP, Chang K, Bloch KD, Zapol WM. Anesthesiology. 2009 Jan;110(1):113-22. doi: 10.1097/ALN.0b013e318190bc4f. PMID: 19104178 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2009Porcine (Pig)

Regional Blood Flow After Serial Normovolemic Exchange Transfusion With HBOC-201 (Hemopure) in Anesthetized Swine

Mongan PD, Moon-Massat PF, Rentko V, Mihok S, Dragovich A, Sharma P · Journal of Trauma

Record details
Authors
Mongan PD, Moon-Massat PF, Rentko V, Mihok S, Dragovich A, Sharma P
Journal
Journal of Trauma
Year
2009
Species / model
Porcine (Pig)
Author institutions
Uniformed Services University
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/ta.0b013e3181838030
PMID
19590308
Original citation
Regional blood flow after serial normovolemic exchange transfusion with HBOC- 201 (Hemopure) in anesthetized swine. Mongan PD, Moon-Massat PF, Rentko V, Mihok S, Dragovich A, Sharma P. J Trauma. 2009 Jul;67(1):51-60. doi: 10.1097/TA.0b013e3181838030. PMID: 19590308 [PubMed - indexed for MEDLINE] Similar articles
2009Porcine (Pig) · Human

Resuscitation with the hemoglobin-based oxygen carrier, HBOC-201, in a swine model of severe uncontrolled hemorrhage and traumatic brain injury

Stern S, Rice J, Philbin N, McGwin G, Arnaud F, Johnson T, Flournoy WS, Ahlers S, Pearce LB, McCarron R, Freilich D · Shock

Record details
Authors
Stern S, Rice J, Philbin N, McGwin G, Arnaud F, Johnson T, Flournoy WS, Ahlers S, Pearce LB, McCarron R, Freilich D
Journal
Shock
Year
2009
Species / model
Porcine (Pig), Human
Author institutions
University of Michigan
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/shk.0b013e3181778dc3
PMID
18497706
Original citation
Resuscitation with the hemoglobin-based oxygen carrier, HBOC-201, in a swine model of severe uncontrolled hemorrhage and traumatic brain injury. Stern S, Rice J, Philbin N, McGwin G, Arnaud F, Johnson T, Flournoy WS, Ahlers S, Pearce LB, McCarron R, Freilich D. Shock. 2009 Jan;31(1):64-79. doi: 10.1097/SHK.0b013e3181778dc3. PMID: 18497706 [PubMed - indexed for MEDLINE] Similar articles
2009Rodent

Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction

Rodriguez C, Vitturi DA, He J, Vandromme M, Brandon A, Hutchings A, Rue LW 3rd, Kerby JD, Patel RP · Biochem J

Record details
Authors
Rodriguez C, Vitturi DA, He J, Vandromme M, Brandon A, Hutchings A, Rue LW 3rd, Kerby JD, Patel RP
Journal
Biochem J
Year
2009
Species / model
Rodent
Author institutions
University of Alabama at Birmingham
Evidence type
Research Support, Non-U.S. Gov't; research-article; Research Support, U.S. Gov't, Non-P.H.S.; Journal Article; Research Support, N.I.H., Extramural
DOI
10.1042/bj20090735
PMID
19555351
Original citation
Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction. Rodriguez C, Vitturi DA, He J, Vandromme M, Brandon A, Hutchings A, Rue LW 3rd, Kerby JD, Patel RP. Biochem J. 2009 Aug 27;422(3):423-32. doi: 10.1042/BJ20090735. PMID: 19555351 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2009Human

The use of Hemopure at Groote Schuur hospital, Cape Town: 4 case studies

Potgieter HE, James MF · Southern African Journal of Anaesthesia and Analgesia

Record details
Authors
Potgieter HE, James MF
Journal
Southern African Journal of Anaesthesia and Analgesia
Year
2009
Species / model
Human
Author institutions
University of Cape Town
Evidence type
Human clinical evidence
DOI
10.1080/22201173.2009.10872581
Original citation
potgieter HE, James MF. The use of Hemopure® at Groote Schuur hospital, Cape Town: 4 case studies. SAJAA 2009; 15(1): 13-15

Title, authors, journal and original publication year checked against the publisher and DOI registration. Not represented as a PubMed-indexed record. The issue year is 2009; platform upload dates of 2010/2014 are not the original publication year.

2008Human

Bovine blood and neuromuscular paralysis as a bridge to recovery in a patient with severe autoimmune hemolytic anemia

Pachinburavan M, Marik PE · Clinical and Translational Science

Record details
Authors
Pachinburavan M, Marik PE
Journal
Clinical and Translational Science
Year
2008
Species / model
Human
Author institutions
Thomas Jefferson University
Evidence type
Human clinical evidence
DOI
10.1111/j.1752-8062.2008.00006.x
PMID
20443842
Original citation
Bovine blood and neuromuscular paralysis as a bridge to recovery in a patient with severe autoimmune hemolytic anemia. Pachinburavan M, Marik PE. Clin Transl Sci. 2008 Sep;1(2):172-3. doi: 10.1111/j.1752-8062.2008.00006.x. PMID: 20443842 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2008Feline (Cat)

Clinical use of a haemoglobin-based oxygen carrying solution (Oxyglobin) in 48 cats (2002-2006)

Weingart C, Kohn B · Journal of Feline Medicine and Surgery

Record details
Authors
Weingart C, Kohn B
Journal
Journal of Feline Medicine and Surgery
Year
2008
Species / model
Feline (Cat)
Author institutions
Free University of Berlin
Evidence type
Journal Article
DOI
10.1016/j.jfms.2007.10.012
PMID
18455461
Original citation
Clinical use of a haemoglobin-based oxygen carrying solution (Oxyglobin) in 48 cats (2002-2006). Weingart C, Kohn B. J Feline Med Surg. 2008 Oct;10(5):431-8. doi: 10.1016/j.jfms.2007.10.012. Epub 2008 May 2. PMID: 18455461 [PubMed - indexed for MEDLINE] Similar articles

Historical product-specific Oxyglobin use in 48 cats, PMID 18455461. Retrospective observational design; does not establish the efficacy or safety of a new BHOC formulation.

2008Rodent · Avian (Bird)

Diagnosis and Treatment of Secondary Anticoagulant Rodenticide Toxicosis in a Red-tailed Hawk (Buteo jamaicensis)

Murray M, Tseng F · Journal of Avian Medicine and Surgery

Record details
Authors
Murray M, Tseng F
Journal
Journal of Avian Medicine and Surgery
Year
2008
Species / model
Rodent, Avian (Bird)
Author institutions
Tufts University
Evidence type
In vitro & analytical evidence
DOI
10.1647/2007-012r.1
PMID
18543601
Original citation
Murray M, Tseng F. Diagnosis and Treatment of Secondary Anticoagulant Rodenticide Toxicosis in a Red-tailed Hawk (Buteo jamaicensis). Journal of Avian Medicine and Surgery. 2008;22(1):41-6.
2008Rodent

Failed induction of heme oxygenase 1 in endothelial cells exposed to the hemoglobin based oxygen carrier Oxyglobin

Rempf C, Ritter A, Schrepfer S, Freitag M, Standl T, Gottschalk A · Artificial Cells, Blood Substitutes, and Biotechnology

Record details
Authors
Rempf C, Ritter A, Schrepfer S, Freitag M, Standl T, Gottschalk A
Journal
Artificial Cells, Blood Substitutes, and Biotechnology
Year
2008
Species / model
Rodent
Author institutions
Knappschaftskrankenhaus Bochum Langendreer
Evidence type
Journal Article
DOI
10.1080/10731190701857769
PMID
18293159
Original citation
Failed induction of heme oxygenase 1 in endothelial cells exposed to the hemoglobin based oxygen carrier Oxyglobin. Rempf C, Ritter A, Schrepfer S, Freitag M, Standl T, Gottschalk A. Artif Cells Blood Substit Immobil Biotechnol. 2008;36(1):34-44. doi: 10.1080/10731190701857769. PMID: 18293159 [PubMed - indexed for MEDLINE] Similar articles
2008Human

HBOC-201 as an alternative to blood transfusion: efficacy and safety evaluation in a multicenter phase III trial in elective orthopedic surgery

Jahr JS, Mackenzie C, Pearce LB, Pitman A, Greenburg AG · Journal of Trauma

Record details
Authors
Jahr JS, Mackenzie C, Pearce LB, Pitman A, Greenburg AG
Journal
Journal of Trauma
Year
2008
Species / model
Human
Author institutions
University of California, Los Angeles
Evidence type
Human clinical evidence
DOI
10.1097/ta.0b013e318173a93f
PMID
18545113
Original citation
HBOC-201 as an alternative to blood transfusion: efficacy and safety evaluation in a multicenter phase III trial in elective orthopedic surgery. Jahr JS, Mackenzie C, Pearce LB, Pitman A, Greenburg AG. J Trauma. 2008 Jun;64(6):1484-97. doi: 10.1097/TA.0b013e318173a93f. PMID: 18545113 [PubMed - indexed for MEDLINE] Similar articles
2008Human

HBOC-201, hemoglobin glutamer-250 (bovine), Hemopure (Biopure Corporation)

Jahr JS, Moallempour M, Lim JC · Expert Opinion on Biological Therapy

Record details
Authors
Jahr JS, Moallempour M, Lim JC
Journal
Expert Opinion on Biological Therapy
Year
2008
Species / model
Human
Author institutions
University of California, Los Angeles
Evidence type
Review; Journal Article
DOI
10.1517/14712598.8.9.1425
PMID
18694360
Original citation
HBOC-201, hemoglobin glutamer-250 (bovine), Hemopure (Biopure Corporation). Jahr JS, Moallempour M, Lim JC. Expert Opin Biol Ther. 2008 Sep;8(9):1425-33. doi: 10.1517/14712598.8.9.1425 . Review. PMID: 18694360 [PubMed - indexed for MEDLINE] Similar articles
2008

HBOC-201: the multi-purpose oxygen therapeutic

Dubé GP, Vranckx P, Greenburg AG · EuroIntervention

Record details
Authors
Dubé GP, Vranckx P, Greenburg AG
Journal
EuroIntervention
Year
2008
Evidence type
Review / Editorial / Policy
PMID
19112795
Original citation
HBOC-201: the multi-purpose oxygen therapeutic. Dubé GP, Vranckx P, Greenburg AG. EuroIntervention. 2008 May;4(1):161-5. Review. PMID: 19112795 [PubMed - indexed for MEDLINE] Similar articles
2008Porcine (Pig)

Hemoglobin-based oxygen carrying compound-201 as salvage therapy for severe neuro- and polytrauma (Injury Severity Score = 27-41)

Dudkiewicz M, Harpaul TA, Proctor KG · Critical Care Medicine

Record details
Authors
Dudkiewicz M, Harpaul TA, Proctor KG
Journal
Critical Care Medicine
Year
2008
Species / model
Porcine (Pig)
Author institutions
University of Miami
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/ccm.0b013e318186f6b3
PMID
18766094
Original citation
Hemoglobin-based oxygen carrying compound-201 as salvage therapy for severe neuro- and polytrauma (Injury Severity Score = 27-41). Dudkiewicz M, Harpaul TA, Proctor KG. Crit Care Med. 2008 Oct;36(10):2838-48. doi: 10.1097/CCM.0b013e318186f6b3. PMID: 18766094 [PubMed - indexed for MEDLINE] Similar articles
2008Rodent

Hemoglobin-Glutamer 200 Reduces Reperfusion Injury of the Cold Preserved Rat Liver by Induction of Heme Oxygenase-1

Topp SA, Krieg A, Koch A, Tidden CM, Ramp U, Hohlfeld T, et al. · Journal of Surgical Research

Record details
Authors
Topp SA, Krieg A, Koch A, Tidden CM, Ramp U, Hohlfeld T, et al.
Journal
Journal of Surgical Research
Year
2008
Species / model
Rodent
Author institutions
University Hospital Düsseldorf
Evidence type
Journal Article
DOI
10.1016/j.jss.2008.02.033
PMID
18395753
Original citation
Hemoglobin-glutamer 200 reduces reperfusion injury of the cold preserved rat liver by induction of heme oxygenase-1. Topp SA, Krieg A, Koch A, Tidden CM, Ramp U, Hohlfeld T, Macher A, Schulte am Esch J 2nd, Eisenberger CF, Stoecklein NH, Knoefel WT. J Surg Res. 2008 Dec;150(2):243-54. doi: 10.1016/j.jss.2008.02.033. Epub 2008 Mar 18. PMID: 18395753 [PubMed - indexed for MEDLINE] Similar articles
2008Human · In vitro / laboratory

Hitachi Hemolytic Index correlates with HBOC-201 concentrations: Impact on suppression of analyte results

Moon-Massat PF, Tierney JP, Hock KG, Scott MG · Clinical Biochemistry

Record details
Authors
Moon-Massat PF, Tierney JP, Hock KG, Scott MG
Journal
Clinical Biochemistry
Year
2008
Species / model
Human, In vitro / laboratory
Author institutions
Biopure Corporation
Evidence type
In vitro & analytical evidence
DOI
10.1016/j.clinbiochem.2007.12.003
PMID
18178161
Original citation
Hitachi Hemolytic Index correlates with HBOC-201 concentrations: impact on suppression of analyte results. Moon-Massat PF, Tierney JP, Hock KG, Scott MG. Clin Biochem. 2008 Apr;41(6):432-5. doi: 10.1016/j.clinbiochem.2007.12.003. Epub 2007 Dec 23. PMID: 18178161 [PubMed - indexed for MEDLINE] Similar articles
2008Ovine (Sheep) · Rodent

Inhaled Nitric Oxide Enables Artificial Blood Transfusion Without Hypertension

Yu B, Raher MJ, Volpato GP, Bloch KD, Ichinose F, Zapol WM · Circulation

Record details
Authors
Yu B, Raher MJ, Volpato GP, Bloch KD, Ichinose F, Zapol WM
Journal
Circulation
Year
2008
Species / model
Ovine (Sheep), Rodent
Author institutions
Harvard Medical School, Massachusetts General Hospital
Evidence type
Preclinical evidence supporting human development
DOI
10.1161/circulationaha.107.729137
PMID
18391111
Original citation
Inhaled nitric oxide enables artificial blood transfusion without hypertension. Yu B, Raher MJ, Volpato GP, Bloch KD, Ichinose F, Zapol WM. Circulation. 2008 Apr 15;117(15):1982-90. doi: 10.1161/CIRCULATIONAHA.107.729137. Epub 2008 Apr 7. PMID: 18391111 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2008Canine (Dog)

Measuring Circulating Blood Volume Using Infused Hemoglobin-Based Oxygen Carrier (Oxyglobin) as an Indicator: Verification in a Canine Hypovolemia Model

Jahr JS, Lurie F, Bezdikian V, Driessen B, Gunther RA · American Journal of Therapeutics

Record details
Authors
Jahr JS, Lurie F, Bezdikian V, Driessen B, Gunther RA
Journal
American Journal of Therapeutics
Year
2008
Species / model
Canine (Dog)
Author institutions
University of California, Los Angeles
Evidence type
Journal Article
DOI
10.1097/mjt.0b013e31804c6f98
PMID
18356627
Original citation
Measuring circulating blood volume using infused hemoglobin-based oxygen carrier (oxyglobin) as an indicator: verification in a canine hypovolemia model. Jahr JS, Lurie F, Bezdikian V, Driessen B, Gunther RA. Am J Ther. 2008 Mar-Apr;15(2):98-101. doi: 10.1097/MJT.0b013e31804c6f98. PMID: 18356627 [PubMed - indexed for MEDLINE] Similar articles
2008Porcine (Pig)

The effects of decreasing low-molecular weight hemoglobin components of hemoglobin-based oxygen carriers in swine with hemorrhagic shock

Rice J, Philbin N, Light R, Arnaud F, Steinbach T, McGwin G, Collier S, Malkevich N, Moon-Massat P, Rentko V, Pearce LB, Ahlers S, McCarron R, Handrigan M, Freilich D · Journal of Trauma

Record details
Authors
Rice J, Philbin N, Light R, Arnaud F, Steinbach T, McGwin G, Collier S, Malkevich N, Moon-Massat P, Rentko V, Pearce LB, Ahlers S, McCarron R, Handrigan M, Freilich D
Journal
Journal of Trauma
Year
2008
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/ta.0b013e318058245e
PMID
18469646
Original citation
The effects of decreasing low-molecular weight hemoglobin components of hemoglobin-based oxygen carriers in swine with hemorrhagic shock. Rice J, Philbin N, Light R, Arnaud F, Steinbach T, McGwin G, Collier S, Malkevich N, Moon-Massatt P, Rentko V, Pearce LB, Ahlers S, McCarron R, Handrigan M, Freilich D. J Trauma. 2008 May;64(5):1240-57. doi: 10.1097/TA.0b013e318058245e. PMID: 18469646 [PubMed - indexed for MEDLINE] Similar articles
2008Porcine (Pig)

Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage

Rosenthal G, Morabito D, Cohen M, Roeytenberg A, Derugin N, Panter SS, et al. · Journal of Neurosurgery

Record details
Authors
Rosenthal G, Morabito D, Cohen M, Roeytenberg A, Derugin N, Panter SS, et al.
Journal
Journal of Neurosurgery
Year
2008
Species / model
Porcine (Pig)
Author institutions
University of California, San Francisco
Evidence type
In vitro & analytical evidence
DOI
10.3171/jns/2008/108/3/0575
PMID
18312106
Original citation
Use of hemoglobin-based oxygen-carrying solution-201 to improve resuscitation parameters and prevent secondary brain injury in a swine model of traumatic brain injury and hemorrhage: laboratory investigation. Rosenthal G, Morabito D, Cohen M, Roeytenberg A, Derugin N, Panter SS, Knudson MM, Manley G. J Neurosurg. 2008 Mar;108(3):575-87. doi: 10.3171/JNS/2008/108/3/0575. PMID: 18312106 [PubMed - indexed for MEDLINE] Similar articles
2007Human

Blood substitutes as pharmacotherapies in clinical practice

Jahr JS, Walker V, Manoochehri K · Current Opinion in Anaesthesiology

Record details
Authors
Jahr JS, Walker V, Manoochehri K
Journal
Current Opinion in Anaesthesiology
Year
2007
Species / model
Human
Author institutions
University of California, Los Angeles
Evidence type
Review; Journal Article
DOI
10.1097/aco.0b013e328172225a
PMID
17620840
Original citation
Blood substitutes as pharmacotherapies in clinical practice. Jahr JS, Walker V, Manoochehri K. Curr Opin Anaesthesiol. 2007 Aug;20(4):325-30. Review. PMID: 17620840 [PubMed - indexed for MEDLINE] Similar articles
2007Human · In vitro / laboratory

Bovine hemoglobin (glutamer-250, Hemopure)-specific immunoglobulin G antibody cross-reacts with human hemoglobin but does not lyse red blood cells in vitro

Hamilton RG, Kickler TS · Transfusion

Record details
Authors
Hamilton RG, Kickler TS
Journal
Transfusion
Year
2007
Species / model
Human, In vitro / laboratory
Author institutions
Johns Hopkins University
Evidence type
Human clinical evidence
DOI
10.1111/j.1537-2995.2007.01176.x
PMID
17381632
Original citation
Bovine hemoglobin (glutamer-250, Hemopure)-specific immunoglobulin G antibody cross-reacts with human hemoglobin but does not lyse red blood cells in vitro. Hamilton RG, Kickler TS. Transfusion. 2007 Apr;47(4):723-8. PMID: 17381632 [PubMed - indexed for MEDLINE] Similar articles
2007

Does OxyVita, a new-generation hemoglobin-based oxygen carrier, or oxyglobin acutely interfere with coagulation compared with normal saline or 6% hetastarch? An ex vivo thromboelastography study

Jahr JS, Weeks DL, Desai P, Lim JC, Butch AW, Gunther R, Driessen B · Journal of Cardiothoracic and Vascular Anesthesia

Record details
Authors
Jahr JS, Weeks DL, Desai P, Lim JC, Butch AW, Gunther R, Driessen B
Journal
Journal of Cardiothoracic and Vascular Anesthesia
Year
2007
Evidence type
Veterinary clinical / research
DOI
10.1053/j.jvca.2007.02.016
PMID
18249328
Original citation
Does OxyVita, a new-generation hemoglobin-based oxygen carrier, or oxyglobin acutely interfere with coagulation compared with normal saline or 6% hetastarch? An ex vivo thromboelastography study. Jahr JS, Weeks DL, Desai P, Lim JC, Butch AW, Gunther R, Driessen B. J Cardiothorac Vasc Anesth. 2008 Feb;22(1):34-9. doi: 10.1053/j.jvca.2007.02.016. Epub 2007 May 24. PMID: 18249328 [PubMed - indexed for MEDLINE] Similar articles
2007Human

Effects of Hemopure on Maximal Oxygen Uptake and Endurance Performance in Healthy Humans

Ashenden M, Schumacher Y, Sharpe K, Varlet-Marie E, Audran M · International Journal of Sports Medicine

Record details
Authors
Ashenden M, Schumacher Y, Sharpe K, Varlet-Marie E, Audran M
Journal
International Journal of Sports Medicine
Year
2007
Species / model
Human
Author institutions
Science and Industry Against Blood Doping Research Consortium
Evidence type
Comparative Study; Research Support, Non-U.S. Gov't; Randomized Controlled Trial; Journal Article
DOI
10.1055/s-2006-924365
PMID
17024639
Original citation
Effects of Hemopure on maximal oxygen uptake and endurance performance in healthy humans. Ashenden MJ, Schumacher YO, Sharpe K, Varlet-Marie E, Audran M. Int J Sports Med. 2007 May;28(5):381-5. Epub 2006 Oct 6. PMID: 17024639 [PubMed - indexed for MEDLINE] Similar articles
2007Canine (Dog)

Effects of low-volume hemoglobin glutamer-200 versus normal saline and arginine vasopressin resuscitation on systemic and skeletal muscle blood flow and oxygenation in a canine hemorrhagic shock model

Driessen B, Zarucco L, Gunther RA, Burns PM, Lamb SV, Vincent SE, Boston RA, Jahr JS, Cheung AT · Critical Care Medicine

Record details
Authors
Driessen B, Zarucco L, Gunther RA, Burns PM, Lamb SV, Vincent SE, Boston RA, Jahr JS, Cheung AT
Journal
Critical Care Medicine
Year
2007
Species / model
Canine (Dog)
Author institutions
University of Pennsylvania
Evidence type
Comparative Study; Research Support, Non-U.S. Gov't; Journal Article; Research Support, N.I.H., Extramural
DOI
10.1097/01.ccm.0000277040.31978.3d
PMID
17581486
Original citation
Effects of low-volume hemoglobin glutamer-200 versus normal saline and arginine vasopressin resuscitation on systemic and skeletal muscle blood flow and oxygenation in a canine hemorrhagic shock model. Driessen B, Zarucco L, Gunther RA, Burns PM, Lamb SV, Vincent SE, Boston RA, Jahr JS, Cheung AT. Crit Care Med. 2007 Sep;35(9):2101-9. PMID: 17581486 [PubMed - indexed for MEDLINE] Similar articles
2007

Hemoglobin-Based O2 Carrier O2 Affinity and Capillary Inlet pO2 Are Important Factors That Influence O2 Transport in a Capillary

Dimino

Record details
Authors
Dimino
Journal
Hemopure
Year
2007
Author institutions
University of Notre Dame
Evidence type
research-article; Journal Article; Research Support, N.I.H., Extramural
DOI
10.1021/bp0700298
PMID
17555329
Original citation
Hemoglobin-based O2 carrier O2 affinity and capillary inlet pO2 are important factors that influence O2 transport in a capillary. Dimino ML, Palmer AF. Biotechnol Prog. 2007 Jul-Aug;23(4):921-31. Epub 2007 Jun 8. PMID: 17555329 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2007Human

Hemopure transfusion in a child with severe anemia

Stefan DC, Uys R, Wessels G · Pediatric Hematology and Oncology

Record details
Authors
Stefan DC, Uys R, Wessels G
Journal
Pediatric Hematology and Oncology
Year
2007
Species / model
Human
Author institutions
Tygerberg Children's Hospital
Evidence type
Human clinical evidence
DOI
10.1080/08880010701360650
PMID
17613869
Original citation
Hemopure transfusion in a child with severe anemia. Stefan DC, Uys R, Wessels G. Pediatr Hematol Oncol. 2007 Jun;24(4):269-73. PMID: 17613869 [PubMed - indexed for MEDLINE] Similar articles
2007Porcine (Pig)

Immune Effects of Decreasing Low-Molecular Weight Hemoglobin Components of Hemoglobin-Based Oxygen Carriers (HBOC) in a Swine Model of Severe Controlled Hemorrhagic Shock

Vandermolen C, Malkevich N, Philbin N, Rice J, Collier S, Hall C, et al. · Artificial Cells, Blood Substitutes, and Biotechnology

Record details
Authors
Vandermolen C, Malkevich N, Philbin N, Rice J, Collier S, Hall C, et al.
Journal
Artificial Cells, Blood Substitutes, and Biotechnology
Year
2007
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1080/10731190701586228
PMID
17922315
Original citation
Immune effects of decreasing low-molecular weight hemoglobin components of hemoglobin-based oxygen carriers (HBOC) in a swine model of severe controlled hemorrhagic shock. VanderMolen C, Malkevich N, Philbin N, Rice J, Collier S, Hall C, Ahlers S, McCarron R, Freilich D, McGwin G, Pearce LB. Artif Cells Blood Substit Immobil Biotechnol. 2007;35(5):507-17. PMID: 17922315 [PubMed - indexed for MEDLINE] Similar articles
2007Porcine (Pig)

Innate Immune Responses in Swine Resuscitated from Severe Traumatic Hemorrhagic Shock with Hemoglobin-Based Oxygen Carrier-201

Hall C, Malkevich N, Handrigan M, Vandermolen C, Aranaud F, Hong J, et al. · Artificial Cells, Blood Substitutes, and Biotechnology

Record details
Authors
Hall C, Malkevich N, Handrigan M, Vandermolen C, Aranaud F, Hong J, et al.
Journal
Artificial Cells, Blood Substitutes, and Biotechnology
Year
2007
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1080/10731190701378568
PMID
17573626
Original citation
Innate immune responses in Swine resuscitated from severe traumatic hemorrhagic shock with hemoglobin-based oxygen carrier-201. Hall C, Malkevich N, Handrigan M, Vandermolen C, Aranaud F, Hong J, Dong F, Rice J, Philbin N, Ahlers S, McCarron R, Freilich D, McGwin G, Flournoy WS, Pearce LB. Artif Cells Blood Substit Immobil Biotechnol. 2007;35(3):259-74. PMID: 17573626 [PubMed - indexed for MEDLINE] Similar articles
2007Porcine (Pig)

Resuscitation from hemorrhagic shock comparing standard hemoglobin-based oxygen carrier (HBOC)-201 versus 7.5% hypertonic HBOC-201

Rivera-Chavez FA, Huerta S, Brown R, York GB, Minei JP · Journal of Trauma

Record details
Authors
Rivera-Chavez FA, Huerta S, Brown R, York GB, Minei JP
Journal
Journal of Trauma
Year
2007
Species / model
Porcine (Pig)
Author institutions
University of Texas Southwestern Medical Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/ta.0b013e3181561157
PMID
17993959
Original citation
Resuscitation from hemorrhagic shock comparing standard hemoglobin-based oxygen carrier (HBOC)-201 versus 7.5% hypertonic HBOC-201. Rivera-Chavez FA, Huerta S, Brown R, York GB, Minei JP. J Trauma. 2007 Nov;63(5):1113-9. PMID: 17993959 [PubMed - indexed for MEDLINE] Similar articles
2007Rodent

Resuscitation from hemorrhagic shock with HBOC-201 in the setting of traumatic brain injury

Kerby JD, Sainz JG, Zhang F, Hutchings A, Sprague S, Farrokhi FR, Son M · Shock

Record details
Authors
Kerby JD, Sainz JG, Zhang F, Hutchings A, Sprague S, Farrokhi FR, Son M
Journal
Shock
Year
2007
Species / model
Rodent
Author institutions
University of Alabama at Birmingham
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.shk.0000248584.10400.dc
PMID
17505305
Original citation
Resuscitation from hemorrhagic shock with HBOC-201 in the setting of traumatic brain injury. Kerby JD, Sainz JG, Zhang F, Hutchings A, Sprague S, Farrokhi FR, Son M. Shock. 2007 Jun;27(6):652-6. PMID: 17505305 [PubMed - indexed for MEDLINE] Similar articles
2006Canine (Dog)

A polymerized bovine hemoglobin oxygen carrier preserves regional myocardial function and reduces infarct size after acute myocardial ischemia

George I, Yi G-H, Schulman AR, Morrow BT, Cheng Y, Gu A, et al. · American Journal of Physiology

Record details
Authors
George I, Yi G-H, Schulman AR, Morrow BT, Cheng Y, Gu A, et al.
Journal
American Journal of Physiology
Year
2006
Species / model
Canine (Dog)
Author institutions
Cardiovascular Research Foundation, Columbia University
Evidence type
Veterinary clinical / research
DOI
10.1152/ajpheart.00076.2006
PMID
16617139
Original citation
A polymerized bovine hemoglobin oxygen carrier preserves regional myocardial function and reduces infarct size after acute myocardial ischemia. George I, Yi GH, Schulman AR, Morrow BT, Cheng Y, Gu A, Zhang G, Oz MC, Burkhoff D, Wang J. Am J Physiol Heart Circ Physiol. 2006 Sep;291(3):H1126-37. Epub 2006 Apr 14. PMID: 16617139 [PubMed - indexed for MEDLINE] Free Article Similar articles
2006Rodent

Acute and long-term effects of modified hemoglobin (HBOC-201) in a rat model of hypertension and chronic kidney disease

Baylis C · Transfusion

Record details
Authors
Baylis C
Journal
Transfusion
Year
2006
Species / model
Rodent
Author institutions
University of Florida
Evidence type
Preclinical evidence supporting human development
DOI
10.1111/j.1537-2995.2006.00858.x
PMID
16836556
Original citation
Acute and long-term effects of modified hemoglobin (HBOC-201) in a rat model of hypertension and chronic kidney disease. Baylis C. Transfusion. 2006 Jul;46(7):1104-11. PMID: 16836556 [PubMed - indexed for MEDLINE] Similar articles
2006Porcine (Pig)

Are i-STAT Results Adversely Affected by an Artificial Blood Substitute In Vivo?

Estrada RR · Military Medicine

Record details
Authors
Estrada RR
Journal
Military Medicine
Year
2006
Species / model
Porcine (Pig)
Author institutions
Wilford Hall Medical Center
Evidence type
Comparative Study; Journal Article
DOI
10.7205/milmed.171.5.381
PMID
16761886
Original citation
Are i-STAT results adversely affected by an artificial blood substitute in vivo? Estrada RR. Mil Med. 2006 May;171(5):381-8. PMID: 16761886 [PubMed - indexed for MEDLINE] Similar articles
2006Rodent

Bovine hemoglobin-based oxygen-carrying solution (HBOC-201) improves flap survival in a rat model of epigastric flap failure

Ortegon DP, Davis MR, Sampson JB, Dick EJ, Kashyap V, Kerby JD · Microsurgery

Record details
Authors
Ortegon DP, Davis MR, Sampson JB, Dick EJ, Kashyap V, Kerby JD
Journal
Microsurgery
Year
2006
Species / model
Rodent
Author institutions
University of Texas Health Science Center at San Antonio
Evidence type
Preclinical evidence supporting human development
DOI
10.1002/micr.20221
PMID
16493668
Original citation
Bovine hemoglobin-based oxygen-carrying solution (HBOC-201) improves flap survival in a rat model of epigastric flap failure. Ortegon DP, Davis MR, Sampson JB, Dick EJ, Kashyap V, Kerby JD. Microsurgery. 2006;26(3):203-6. PMID: 16493668 [PubMed - indexed for MEDLINE] Similar articles
2006Porcine (Pig)

Bovine polymerized hemoglobin (hemoglobin-based oxygen carrier-201) resuscitation in three swine models of hemorrhagic shock with militarily relevant delayed evacuation-Effects on histopathology and organ function

Johnson T, Arnaud F, Dong F, Philbin N, Rice J, Asher L, et al. · Critical Care Medicine

Record details
Authors
Johnson T, Arnaud F, Dong F, Philbin N, Rice J, Asher L, et al.
Journal
Critical Care Medicine
Year
2006
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.ccm.0000215824.85190.89
PMID
16540964
Original citation
Bovine polymerized hemoglobin (hemoglobin-based oxygen carrier-201) resuscitation in three swine models of hemorrhagic shock with militarily relevant delayed evacuation--effects on histopathology and organ function. Johnson T, Arnaud F, Dong F, Philbin N, Rice J, Asher L, Arrisueno M, Warndorf M, Gurney J, McGwin G, Kaplan L, Flournoy WS, Apple FS, Pearce LB, Ahlers S, McCarron R, Freilich D. Crit Care Med. 2006 May;34(5):1464-74. PMID: 16540964 [PubMed - indexed for MEDLINE] Similar articles
2006Porcine (Pig)

Bovine Polymerized Hemoglobin Versus Hextend Resuscitation in a Swine Model of Severe Controlled Hemorrhagic Shock with Delay to Definitive Care

Rice J, Philbin N, McGwin G, Arnaud F, Johnson T, Flournoy WS, et al. · Shock

Record details
Authors
Rice J, Philbin N, McGwin G, Arnaud F, Johnson T, Flournoy WS, et al.
Journal
Shock
Year
2006
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.shk.0000226338.48033.c2
PMID
16912657
Original citation
Bovine polymerized hemoglobin versus Hextend resuscitation in a swine model of severe controlled hemorrhagic shock with delay to definitive care. Rice J, Philbin N, McGwin G, Arnaud F, Johnson T, Flournoy WS, Pearce LB, McCarron R, Kaplan L, Handrigan M, Freilich D. Shock. 2006 Sep;26(3):302-10. PMID: 16912657 [PubMed - indexed for MEDLINE] Similar articles
2006Canine (Dog)

Effects of isovolemic resuscitation with hemoglobin-based oxygen carrier Hemoglobin glutamer-200 (bovine) on systemic and mesenteric perfusion and oxygenation in a canine model of hemorrhagic shock

Driessen B, Jahr J, Lurie F, Gunther R · Veterinary Anaesthesia and Analgesia

Record details
Authors
Driessen B, Jahr J, Lurie F, Gunther R
Journal
Veterinary Anaesthesia and Analgesia
Year
2006
Species / model
Canine (Dog)
Author institutions
University of Pennsylvania
Evidence type
Research Support, Non-U.S. Gov't; Journal Article; Research Support, N.I.H., Extramural
DOI
10.1111/j.1467-2995.2005.00280.x
PMID
17083609
Original citation
Effects of isovolemic resuscitation with hemoglobin-based oxygen carrier Hemoglobin glutamer-200 (bovine) on systemic and mesenteric perfusion and oxygenation in a canine model of hemorrhagic shock: a comparison with 6% hetastarch solution and shed blood. Driessen B, Jahr JS, Lurie F, Gunther RA. Vet Anaesth Analg. 2006 Nov;33(6):368-80. PMID: 17083609 [PubMed - indexed for MEDLINE] Similar articles
2006Rodent

Hemoglobin-Based Oxygen Carrier Does Not Improve Survival of Ischemic Rat Island Groin Flaps

Hofeling AD, Bello G, Jackson I, Jackson AH, Kim E · Journal of Investigative Surgery

Record details
Authors
Hofeling AD, Bello G, Jackson I, Jackson AH, Kim E
Journal
Journal of Investigative Surgery
Year
2006
Species / model
Rodent
Author institutions
Michigan Veterinary Specialists
Evidence type
Evaluation Study; Journal Article
DOI
10.1080/08941930600889417
PMID
16966208
Original citation
Hemoglobin-based oxygen carrier does not improve survival of ischemic rat island groin flaps. Hofeling AD, Bello G, Jackson I, Jackson AH, Kim E. J Invest Surg. 2006 Sep-Oct;19(5):299-305. PMID: 16966208 [PubMed - indexed for MEDLINE] Similar articles
2006Porcine (Pig)

Immune effects of resuscitation with HBOC-201, a hemoglobin-based oxygen carrier, in swine with moderately severe hemorrhagic shock from controlled hemorrhage

Dong F, Hall CH, Golech SA, et al. · Shock

Record details
Authors
Dong F, Hall CH, Golech SA, et al.
Journal
Shock
Year
2006
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.shk.0000187982.56030.94
PMID
16369186
Original citation
Immune effects of resuscitation with HBOC-201, a hemoglobin-based oxygen carrier, in swine with moderately severe hemorrhagic shock from controlled hemorrhage. Dong F, Hall CH, Golech SA, Philbin NB, Rice JP, Gurney J, Arnaud FG, Hammett M, Ma X, Flournoy WS, Hong J, Kaplan LJ, Pearce LB, McGwin G, Ahlers S, McCarron R, Freilich D. Shock. 2006 Jan;25(1):50-5. PMID: 16369186 [PubMed - indexed for MEDLINE] Similar articles
2006Porcine (Pig)

Improvement of impaired microcirculation and tissue oxygenation by hemodilution with hydroxyethyl starch plus cell-free hemoglobin in acute porcine pancreatitis

Freitag M, Standl TG, Kleinhans H, Gottschalk A, Mann O, Rempf C, et al. · Pancreatology

Record details
Authors
Freitag M, Standl TG, Kleinhans H, Gottschalk A, Mann O, Rempf C, et al.
Journal
Pancreatology
Year
2006
Species / model
Porcine (Pig)
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Journal Article
DOI
10.1159/000091962
PMID
16534248
Original citation
Improvement of impaired microcirculation and tissue oxygenation by hemodilution with hydroxyethyl starch plus cell-free hemoglobin in acute porcine pancreatitis. Freitag M, Standl TG, Kleinhans H, Gottschalk A, Mann O, Rempf C, Bachmann K, Gocht A, Petri S, Izbicki JR, Strate T. Pancreatology. 2006;6(3):232-9. Epub 2006 Mar 9. PMID: 16534248 [PubMed - indexed for MEDLINE] Similar articles
2006Porcine (Pig)

Prehospital HBOC-201 After Traumatic Brain Injury and Hemorrhagic Shock in Swine

Patel MB, Feinstein AJ, Saenz AD, Majetschak M, Proctor KG · Journal of Trauma

Record details
Authors
Patel MB, Feinstein AJ, Saenz AD, Majetschak M, Proctor KG
Journal
Journal of Trauma
Year
2006
Species / model
Porcine (Pig)
Author institutions
University of Miami
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.ta.0000219730.71206.3a
PMID
16832248
Original citation
Prehospital HBOC-201 after traumatic brain injury and hemorrhagic shock in swine. Patel MB, Feinstein AJ, Saenz AD, Majetschak M, Proctor KG. J Trauma. 2006 Jul;61(1):46-56. PMID: 16832248 [PubMed - indexed for MEDLINE] Similar articles
2006Human

South Africa: clinical experience with Hemopure

Levien LJ · ISBT Science Series

Record details
Authors
Levien LJ
Journal
ISBT Science Series
Year
2006
Species / model
Human
Author institutions
Milpark Hospital
Evidence type
Human clinical evidence
DOI
10.1111/j.1751-2824.2006.00025.x
Original citation
Levien LJ. South Africa: clinical experience with Hemopure. ISBT Science Series. 2006;1(1):167–173. doi: 10.1111/j.1751-2824.2006.00025.x.

Title, authors, journal and original publication year checked against the publisher and DOI registration. Not represented as a PubMed-indexed record.

2006Canine (Dog)

Systemic function, oxygenation and microvascular correlation during treatment of hemorrhagic shock with blood substitutes

Cheung AT, Duong PL, Driessen B, Chen PC, Jahr JS, Gunther RA · Clinical Hemorheology and Microcirculation

Record details
Authors
Cheung AT, Duong PL, Driessen B, Chen PC, Jahr JS, Gunther RA
Journal
Clinical Hemorheology and Microcirculation
Year
2006
Species / model
Canine (Dog)
Author institutions
University of California, Davis
Evidence type
Comparative Study; Research Support, Non-U.S. Gov't; Journal Article; Research Support, N.I.H., Extramural
PMID
16543653
Original citation
Systemic function, oxygenation and microvascular correlation during treatment of hemorrhagic shock with blood substitutes. Cheung AT, Duong PL, Driessen B, Chen PC, Jahr JS, Gunther RA. Clin Hemorheol Microcirc. 2006;34(1-2):325-34. PMID: 16543653 [PubMed - indexed for MEDLINE] Similar articles
2006Porcine (Pig)

Vasoactivity of Bovine Polymerized Hemoglobin (HBOC-201) in Swine With Traumatic Hemorrhagic Shock With and Without Brain Injury

Rice J, Philbin N, Handrigan M, Hall C, McGwin G, Ahlers S, et al. · Journal of Trauma

Record details
Authors
Rice J, Philbin N, Handrigan M, Hall C, McGwin G, Ahlers S, et al.
Journal
Journal of Trauma
Year
2006
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.ta.0000236640.62893.fa
PMID
17099513
Original citation
Vasoactivity of bovine polymerized hemoglobin (HBOC-201) in swine with traumatic hemorrhagic shock with and without brain injury. Rice J, Philbin N, Handrigan M, Hall C, McGwin G, Ahlers S, Pearce LB, Arnaud F, McCarron R, Freilich D. J Trauma. 2006 Nov;61(5):1085-99. PMID: 17099513 [PubMed - indexed for MEDLINE] Similar articles
2005Porcine (Pig)

A hemoglobin-based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus hetastarch (HEX) in a moderate severity hemorrhagic shock swine model with delayed evacuation

Philbin N, Rice J, Gurney J, McGwin G, Arnaud F, Dong F, et al. · Resuscitation

Record details
Authors
Philbin N, Rice J, Gurney J, McGwin G, Arnaud F, Dong F, et al.
Journal
Resuscitation
Year
2005
Species / model
Porcine (Pig)
Author institutions
Naval Medical Research Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1016/j.resuscitation.2005.03.019
PMID
16081200
Original citation
A hemoglobin-based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus hetastarch (HEX) in a moderate severity hemorrhagic shock swine model with delayed evacuation. Philbin N, Rice J, Gurney J, McGwin G, Arnaud F, Dong F, Johnson T, Flournoy WS, Ahlers S, Pearce LB, McCarron R, Freilich D. Resuscitation. 2005 Sep;66(3):367-78. PMID: 16081200 [PubMed - indexed for MEDLINE] Similar articles
2005Human

A new oxygen transport agent

Standl T · Haematologica

Record details
Authors
Standl T
Journal
Haematologica
Year
2005
Species / model
Human
Author institutions
Academic Hospital Solingen
Evidence type
Comment; Journal Article
PMID
15820934
Original citation
Standl T. A new oxygen transport agent. Haematologica. 2005 Apr;90(4):437-8.
2005Canine (Dog) · In vitro / laboratory

Does Methemoglobin from Oxidized Hemoglobin-Based Oxygen Carrier (Hemoglobin Glutamer-200) Interfere with Lactate Measurement (YSI 2700 SELECT Biochemistry Analyzer)?

Osgood SL, Jahr JS, Desai P, Tsukamoto J, Driessen B · Anesthesia & Analgesia

Record details
Authors
Osgood SL, Jahr JS, Desai P, Tsukamoto J, Driessen B
Journal
Anesthesia & Analgesia
Year
2005
Species / model
Canine (Dog), In vitro / laboratory
Author institutions
Charles R. Drew University of Medicine and Science, University of California, Los Angeles, University of Pennsylvania
Evidence type
Journal Article
DOI
10.1213/01.ane.0000143337.05366.cd
PMID
15673872
Original citation
Does methemoglobin from oxidized hemoglobin-based oxygen carrier (hemoglobin Glutamer-200) interfere with lactate measurement (YSI 2700 SELECT Biochemistry Analyzer)? Osgood SL, Jahr JS, Desai P, Tsukamoto J, Driessen B. Anesth Analg. 2005 Feb;100(2):437-9. PMID: 15673872 [PubMed - indexed for MEDLINE] Similar articles
2005Rodent · Human

Effects of prophylactic or therapeutic application of bovine haemoglobin HBOC-200 on ischaemia-reperfusion injury following acute coronary ligature in rats

Burmeister MA, Rempf C, Standl TG, Rehberg S, Bartsch-Zwemke S, Krause T, Tuszynski S, Gottschalk A, Schulte am Esch J · British Journal of Anaesthesia

Record details
Authors
Burmeister MA, Rempf C, Standl TG, Rehberg S, Bartsch-Zwemke S, Krause T, Tuszynski S, Gottschalk A, Schulte am Esch J
Journal
British Journal of Anaesthesia
Year
2005
Species / model
Rodent, Human
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Journal Article
DOI
10.1093/bja/aei255
PMID
16227339
Original citation
Effects of prophylactic or therapeutic application of bovine haemoglobin HBOC- 200 on ischaemia-reperfusion injury following acute coronary ligature in rats. Burmeister MA, Rempf C, Standl TG, Rehberg S, Bartsch-Zwemke S, Krause T, Tuszynski S, Gottschalk A, Schulte am Esch J. Br J Anaesth. 2005 Dec;95(6):737-45. Epub 2005 Oct 14. PMID: 16227339 [PubMed - indexed for MEDLINE] Free Article Similar articles
2005Canine (Dog)

Enhanced central organ oxygenation after application of bovine cell-free hemoglobin HBOC-201

Freitag M, Standl TG, Gottschalk A, Burmeister MA, Rempf C, Horn EP, et al. · Canadian Journal of Anesthesia

Record details
Authors
Freitag M, Standl TG, Gottschalk A, Burmeister MA, Rempf C, Horn EP, et al.
Journal
Canadian Journal of Anesthesia
Year
2005
Species / model
Canine (Dog)
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Preclinical evidence supporting human development
DOI
10.1007/bf03022050
PMID
16251554
Original citation
Enhanced central organ oxygenation after application of bovine cell-free hemoglobin HBOC-201. Freitag M, Standl TG, Gottschalk A, Burmeister MA, Rempf C, Horn EP, Strate T, Schulte Am Esch J. Can J Anaesth. 2005 Nov;52(9):904-14. PMID: 16251554 [PubMed - indexed for MEDLINE] Similar articles
2005

Hemopure's Process Demonstrates TSE and Viral Clearance

Laccetti A, Bagai J, Gawryl MS, Light WR

Record details
Authors
Laccetti A, Bagai J, Gawryl MS, Light WR
Journal
Advances in Transfusion Safety
Year
2005
Author institutions
Biopure Corporation
Evidence type
Journal Article
PMID
16050153
Original citation
Hemopure's process demonstrates TSE and viral clearance. Laccetti A, Bagai J, Gawryl MS, Light WR. Dev Biol (Basel). 2005;120:35-6. No abstract available. PMID: 16050153 [PubMed - indexed for MEDLINE] Similar articles
2005Rodent

Influence of the Hemoglobin Solution HBOC-201 on Tissue Oxygenation in the Rat R1H-Tumor

Gottschalk A, Raabe A, Hommel M, Rempf C, Freitag M, Standl T

Record details
Authors
Gottschalk A, Raabe A, Hommel M, Rempf C, Freitag M, Standl T
Journal
Nonclinical
Year
2005
Species / model
Rodent
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Preclinical evidence supporting human development
DOI
10.1080/10731190500289750
PMID
16317957
Original citation
Influence of the hemoglobin solution HBOC-201 on tissue oxygenation in the rat R1H-tumor. Gottschalk A, Raabe A, Hommel M, Rempf C, Freitag M, Standl T. Artif Cells Blood Substit Immobil Biotechnol. 2005;33(4):379-89. PMID: 16317957 [PubMed - indexed for MEDLINE] Similar articles
2005Human · In vitro / laboratory

Lactate Measurement Interference by Hemoglobin-Based Oxygen Carriers (Oxyglobin, Hemopure, and Hemolink)

Jahr JS, Osgood S, Rothenberg SJ, Li Q-L, Butch AW, Gunther R, et al. · Anesthesia & Analgesia

Record details
Authors
Jahr JS, Osgood S, Rothenberg SJ, Li Q-L, Butch AW, Gunther R, et al.
Journal
Anesthesia & Analgesia
Year
2005
Species / model
Human, In vitro / laboratory
Author institutions
Charles R. Drew University of Medicine and Science, Johns Hopkins University, National Institute of Public Health, Mexico, University of California, Davis, University of California, Los Angeles, University of Pennsylvania
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.1213/01.ane.0000142116.42938.82
PMID
15673871
Original citation
Lactate measurement interference by hemoglobin-based oxygen carriers (Oxyglobin, Hemopure, and Hemolink). Jahr JS, Osgood S, Rothenberg SJ, Li QL, Butch AW, Gunther R, Cheung A, Driessen B. Anesth Analg. 2005 Feb;100(2):431-6. PMID: 15673871 [PubMed - indexed for MEDLINE] Similar articles
2005Human

N-Terminal Adducts of Bovine Hemoglobin with Glutaraldehyde in a Hemoglobin-Based Oxygen Carrier

Gasthuys M, Alves S, Tabet J-C · Analytical Chemistry

Record details
Authors
Gasthuys M, Alves S, Tabet J-C
Journal
Analytical Chemistry
Year
2005
Species / model
Human
Author institutions
University Pierre et Marie Curie
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.1021/ac048107i
PMID
15889931
Original citation
N-terminal adducts of bovine hemoglobin with glutaraldehyde in a hemoglobin- based oxygen carrier. Gasthuys M, Alves S, Tabet JC. Anal Chem. 2005 May 15;77(10):3372-8. PMID: 15889931 [PubMed - indexed for MEDLINE] Similar articles
2005Rodent

No Effect of the Hemoglobin Solution HBOC-201 on the Response of the Rat R1H Tumor to Fractionated Irradiation

Raabe A, Gottschalk A, Hommel M, Dubben H-H, Standl T · Strahlentherapie und Onkologie

Record details
Authors
Raabe A, Gottschalk A, Hommel M, Dubben H-H, Standl T
Journal
Strahlentherapie und Onkologie
Year
2005
Species / model
Rodent
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Preclinical evidence supporting human development
DOI
10.1007/s00066-005-1418-3
PMID
16254709
Original citation
No effect of the hemoglobin solution HBOC-201 on the response of the rat R1H tumor to fractionated irradiation. Raabe A, Gottschalk A, Hommel M, Dubben HH, Strandl T. Strahlenther Onkol. 2005 Nov;181(11):730-7. PMID: 16254709 [PubMed - indexed for MEDLINE] Similar articles
2005Porcine (Pig)

Prolonged Low-Volume Resuscitation with HBOC-201 in a Large-Animal Survival Model of Controlled Hemorrhage

Fitzpatrick CM, Biggs KL, Atkins BZ, et al. · Journal of Trauma

Record details
Authors
Fitzpatrick CM, Biggs KL, Atkins BZ, et al.
Journal
Journal of Trauma
Year
2005
Species / model
Porcine (Pig)
Author institutions
Wilford Hall Medical Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.ta.0000174730.62338.88
PMID
16294065
Original citation
Prolonged low-volume resuscitation with HBOC-201 in a large-animal survival model of controlled hemorrhage. Fitzpatrick CM, Biggs KL, Atkins BZ, Quance-Fitch FJ, Dixon PS, Savage SA, Jenkins DH, Kerby JD. J Trauma. 2005 Aug;59(2):273-81; discussion 281-3. PMID: 16294065 [PubMed - indexed for MEDLINE] Similar articles
2005Porcine (Pig)

Resuscitation with a hemoglobin-based oxygen carrier after traumatic brain injury

King DR, Cohn SM, Proctor KG · Journal of Trauma

Record details
Authors
King DR, Cohn SM, Proctor KG
Journal
Journal of Trauma
Year
2005
Species / model
Porcine (Pig)
Author institutions
University of Miami
Evidence type
Preclinical evidence supporting human development
PMID
16361895
Original citation
Resuscitation with a hemoglobin-based oxygen carrier after traumatic brain injury. King DR, Cohn SM, Proctor KG. J Trauma. 2005 Sep;59(3):553-60; discussion 560-2. PMID: 16361895 [PubMed - indexed for MEDLINE] Similar articles
2005Equine (Horse)

The Pharmacokinetics of Hemoglobin-Based Oxygen Carrier Hemoglobin Glutamer-200 Bovine in the Horse

Soma LR, Uboh CE, Guan F, Luo Y, Moate PJ, Boston RC, et al. · Anesthesia & Analgesia

Record details
Authors
Soma LR, Uboh CE, Guan F, Luo Y, Moate PJ, Boston RC, et al.
Journal
Anesthesia & Analgesia
Year
2005
Species / model
Equine (Horse)
Author institutions
University of California, Los Angeles, University of Pennsylvania
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.1213/01.ane.0000154081.38466.09
PMID
15920176
Original citation
The pharmacokinetics of hemoglobin-based oxygen carrier hemoglobin glutamer- 200 bovine in the horse. Soma LR, Uboh CE, Guan F, Luo Y, Moate PJ, Boston RC, Driessen B. Anesth Analg. 2005 Jun;100(6):1570-5. PMID: 15920176 [PubMed - indexed for MEDLINE] Similar articles
2004

A hemoglobin based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus Hetastarch (HEX) in an uncontrolled liver injury hemorrhagic shock swine model with delayed evacuation

Gurney J, Philbin N, Rice J, Arnaud F, Dong F, Wulster-Radcliffe M, Pearce LB, Kaplan L, McCarron R, Freilich D · Journal of Trauma

Record details
Authors
Gurney J, Philbin N, Rice J, Arnaud F, Dong F, Wulster-Radcliffe M, Pearce LB, Kaplan L, McCarron R, Freilich D
Journal
Journal of Trauma
Year
2004
Evidence type
Preclinical evidence supporting human development
PMID
15514525
Original citation
A hemoglobin based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus Hetastarch (HEX) in an uncontrolled liver injury hemorrhagic shock swine model with delayed evacuation. Gurney J, Philbin N, Rice J, Arnaud F, Dong F, Wulster-Radcliffe M, Pearce LB, Kaplan L, McCarron R, Freilich D. J Trauma. 2004 Oct;57(4):726-38. PMID: 15514525 [PubMed - indexed for MEDLINE] Similar articles
2004Human

Hemoglobin-based oxygen carriers

Greenburg GA, Kim HW · Critical Care

Record details
Authors
Greenburg GA, Kim HW
Journal
Critical Care
Year
2004
Species / model
Human
Author institutions
Brown University
Evidence type
Reviews, clinical context & policy
DOI
10.1186/cc2455
PMID
15196328
Original citation
Hemoglobin-based oxygen carriers. Greenburg AG, Kim HW. Crit Care. 2004;8 Suppl 2:S61-4. Epub 2004 Jun 14. Review. PMID: 15196328 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2004Porcine (Pig)

Resuscitation with a blood substitute causes vasoconstriction without nitric oxide scavenging in a model of arterial hemorrhage

Fitzpatrick C, Savage S, Kerby J, Clouse W, Kashyap V · Journal of the American College of Surgeons

Record details
Authors
Fitzpatrick C, Savage S, Kerby J, Clouse W, Kashyap V
Journal
Journal of the American College of Surgeons
Year
2004
Species / model
Porcine (Pig)
Author institutions
Wilford Hall Medical Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1016/j.jamcollsurg.2004.07.025
PMID
15501108
Original citation
Resuscitation with a blood substitute causes vasoconstriction without nitric oxide scavenging in a model of arterial hemorrhage. Fitzpatrick CM, Savage SA, Kerby JD, Clouse WD, Kashyap VS. J Am Coll Surg. 2004 Nov;199(5):693-701. PMID: 15501108 [PubMed - indexed for MEDLINE] Similar articles
2004Human · In vitro / laboratory

The Effect of Hemopure on Coagulation in Clinically Relevant Concentrations

James MF, Potgieter HE, Ellis P · Anesthesia & Analgesia

Record details
Authors
James MF, Potgieter HE, Ellis P
Journal
Anesthesia & Analgesia
Year
2004
Species / model
Human, In vitro / laboratory
Author institutions
Groote Schuur Hospital, University of Cape Town
Evidence type
Journal Article
DOI
10.1213/01.ane.0000136477.46472.eb
PMID
15562038
Original citation
The effect of hemopure on coagulation in clinically relevant concentrations. James MF, Potgieter HE, Ellis P. Anesth Analg. 2004 Dec;99(6):1593-7, table of contents. PMID: 15562038 [PubMed - indexed for MEDLINE] Similar articles
2004Porcine (Pig)

The use of a hemoglobin-based oxygen-carrying solution (HBOC-201) for extracorporeal membrane oxygenation in a porcine model with acute respiratory distress syndrome

Henderson CL, Anderson CM, Sorrells DL, Wilson BJ, Dick EJ, DiGeronimo RJ · Pediatric Critical Care Medicine

Record details
Authors
Henderson CL, Anderson CM, Sorrells DL, Wilson BJ, Dick EJ, DiGeronimo RJ
Journal
Pediatric Critical Care Medicine
Year
2004
Species / model
Porcine (Pig)
Author institutions
Wilford Hall Medical Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.pcc.0000123544.46047.ba
PMID
15215011
Original citation
The use of a hemoglobin-based oxygen-carrying solution (HBOC-201) for extracorporeal membrane oxygenation in a porcine model with acute respiratory distress syndrome. Henderson CL, Anderson CM, Sorrells DL, Wilson BJ, Dick EJ, DiGeronimo RJ. Pediatr Crit Care Med. 2004 Jul;5(4):384-90. PMID: 15215011 [PubMed - indexed for MEDLINE] Similar articles
2004Avian (Bird) · Other animal

Transfusion Medicine in Exotic Pets

Lichtenberger M · Clinical Techniques in Small Animal Practice

Record details
Authors
Lichtenberger M
Journal
Clinical Techniques in Small Animal Practice
Year
2004
Species / model
Avian (Bird), Other animal
Author institutions
Animal Emergency Center, Glendale
Evidence type
Review; Journal Article
DOI
10.1053/j.ctsap.2004.01.006
PMID
15179929
Original citation
Transfusion medicine in exotic pets. Lichtenberger M. Clin Tech Small Anim Pract. 2004 May;19(2):88-95. Review. PMID: 15179929 [PubMed - indexed for MEDLINE] Similar articles
2004Human

Unique Tryptic Peptides Specific for Bovine and Human Hemoglobin in the Detection and Confirmation of Hemoglobin-Based Oxygen Carriers

Guan F, Uboh C, Soma L, Luo Y, Driessen B · Analytical Chemistry

Record details
Authors
Guan F, Uboh C, Soma L, Luo Y, Driessen B
Journal
Analytical Chemistry
Year
2004
Species / model
Human
Author institutions
University of Pennsylvania
Evidence type
Journal Article
DOI
10.1021/ac035425t
PMID
15373451
Original citation
Unique tryptic peptides specific for bovine and human hemoglobin in the detection and confirmation of hemoglobin-based oxygen carriers. Guan F, Uboh C, Soma L, Luo Y, Driessen B. Anal Chem. 2004 Sep 1;76(17):5118-26. PMID: 15373451 [PubMed - indexed for MEDLINE] Similar articles
2003

A comparison of the hemoglobin-based oxygen carrier HBOC-201 to other low- volume resuscitation fluids in a model of controlled hemorrhagic shock

Sampson JB, Davis MR, Mueller DL, Kashyap VS, Jenkins DH, Kerby JD · Journal of Trauma

Record details
Authors
Sampson JB, Davis MR, Mueller DL, Kashyap VS, Jenkins DH, Kerby JD
Journal
Journal of Trauma
Year
2003
Evidence type
Pending full-text classification
PMID
14566133
Original citation
A comparison of the hemoglobin-based oxygen carrier HBOC-201 to other low- volume resuscitation fluids in a model of controlled hemorrhagic shock. Sampson JB, Davis MR, Mueller DL, Kashyap VS, Jenkins DH, Kerby JD. J Trauma. 2003 Oct;55(4):747-54. PMID: 14566133 [PubMed - indexed for MEDLINE] Similar articles
2003Canine (Dog)

Arterial oxygenation and oxygen delivery after hemoglobin-based oxygen carrier infusion in canine hypovolemic shock: A dose-response study

Driessen B, Jahr JS, Lurie F, Golkaryeh MS, Gunther RA · Critical Care Medicine

Record details
Authors
Driessen B, Jahr JS, Lurie F, Golkaryeh MS, Gunther RA
Journal
Critical Care Medicine
Year
2003
Species / model
Canine (Dog)
Author institutions
University of Pennsylvania
Evidence type
Comparative Study; Research Support, U.S. Gov't, P.H.S.; Research Support, Non-U.S. Gov't; Evaluation Study; Journal Article
DOI
10.1097/01.ccm.0000063476.79749.c1
PMID
12794419
Original citation
Arterial oxygenation and oxygen delivery after hemoglobin-based oxygen carrier infusion in canine hypovolemic shock: a dose-response study. Driessen B, Jahr JS, Lurie F, Golkaryeh MS, Gunther RA. Crit Care Med. 2003 Jun;31(6):1771-9. PMID: 12794419 [PubMed - indexed for MEDLINE] Similar articles
2003Ovine (Sheep)

Colloid osmotic pressure after hemorrhage and replenishment with Oxyglobin Solution, hetastarch, or whole blood in pregnant sheep

Posner LP, Moon PF, Bliss SP, Gleed RD, Erb HN · Veterinary Anaesthesia and Analgesia

Record details
Authors
Posner LP, Moon PF, Bliss SP, Gleed RD, Erb HN
Journal
Veterinary Anaesthesia and Analgesia
Year
2003
Species / model
Ovine (Sheep)
Author institutions
Cornell University
Evidence type
Comparative Study; Clinical Trial; Randomized Controlled Trial; Journal Article
DOI
10.1046/j.1467-2995.2003.00088.x
PMID
14498915
Original citation
Colloid osmotic pressure after hemorrhage and replenishment with Oxyglobin Solution, hetastarch, or whole blood in pregnant sheep. Posner LP, Moon PF, Bliss SP, Gleed RD, Erb HN. Vet Anaesth Analg. 2003 Jan;30(1):30-6. PMID: 14498915 [PubMed - indexed for MEDLINE] Similar articles
2003Canine (Dog)

Hemoglobin-based oxygen carrier HBOC-201 provides higher and faster increase in oxygen tension in skeletal muscle of anemic dogs than do stored red blood cells

Standl T, Freitag M, Burmeister M, Horn E, Wilhelm S, Esch JA · Journal of Vascular Surgery

Record details
Authors
Standl T, Freitag M, Burmeister M, Horn E, Wilhelm S, Esch JA
Journal
Journal of Vascular Surgery
Year
2003
Species / model
Canine (Dog)
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Comparative Study; Evaluation Study; Journal Article
DOI
10.1067/mva.2003.127
PMID
12663989
Original citation
Hemoglobin-based oxygen carrier HBOC-201 provides higher and faster increase in oxygen tension in skeletal muscle of anemic dogs than do stored red blood cells. Standl T, Freitag M, Burmeister MA, Horn EP, Wilhelm S, Am Esch JS. J Vasc Surg. 2003 Apr;37(4):859-65. PMID: 12663989 [PubMed - indexed for MEDLINE] Free Article Similar articles
2003Porcine (Pig)

Low-Volume Resuscitation with a Polymerized Bovine Hemoglobin-Based Oxygen-Carrying Solution (HBOC-201) Provides Adequate Tissue Oxygenation for Survival in a Porcine Model of Controlled Hemorrhage

York GB, Eggers JS, Smith DL, Jenkins DH, McNeil JD, Mueller D, Josephs JD, Kerby JD · Journal of Trauma

Record details
Authors
York GB, Eggers JS, Smith DL, Jenkins DH, McNeil JD, Mueller D, Josephs JD, Kerby JD
Journal
Journal of Trauma
Year
2003
Species / model
Porcine (Pig)
Author institutions
Wilford Hall Medical Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/01.ta.0000092681.17874.6f
PMID
14608160
Original citation
Low-volume resuscitation with a polymerized bovine hemoglobin-based oxygen- carrying solution (HBOC-201) provides adequate tissue oxygenation for survival in a porcine model of controlled hemorrhage. York GB, Eggers JS, Smith DL, Jenkins DH, McNeil JD, Mueller D, Josephs JD, Kerby JD. J Trauma. 2003 Nov;55(5):873-85. PMID: 14608160 [PubMed - indexed for MEDLINE] Similar articles
2003

Oxygen therapeutics (blood substitutes) in cardiac surgery

Mosa MM, Cheng DC · Current Opinion in Anaesthesiology

Record details
Authors
Mosa MM, Cheng DC
Journal
Current Opinion in Anaesthesiology
Year
2003
Author institutions
London Health Sciences Center, University of Western Ontario
Evidence type
Pending full-text classification
DOI
10.1097/00001503-200302000-00004
PMID
17021438
Original citation
Oxygen therapeutics (blood substitutes) in cardiac surgery. Mosa MM, Cheng DC. Curr Opin Anaesthesiol. 2003 Feb;16(1):21-6. PMID: 17021438 [PubMed] Similar articles
2003

Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation

Manley GT, Hemphill JC, Morabito D, Erickson V, Holcroft JJ, Derugin N, Knudson MM · Adv Exp Med Biol

Record details
Authors
Manley GT, Hemphill JC, Morabito D, Erickson V, Holcroft JJ, Derugin N, Knudson MM
Journal
Adv Exp Med Biol
Year
2003
Evidence type
Pending full-text classification
PMID
14562727
Original citation
Small-volume resuscitation with the hemoglobin substitute HBOC-201: effect on brain tissue oxygenation. Manley GT, Hemphill JC, Morabito D, Erickson V, Holcroft JJ, Derugin N, Knudson MM. Adv Exp Med Biol. 2003;530:311-7. PMID: 14562727 [PubMed - indexed for MEDLINE] Similar articles
2003Rodent

Systemic Intravenous Infusion of Bovine Hemoglobin Significantly Reduces Microcirculatory Dysfunction in Experimentally Induced Pancreatitis in the Rat

Strate T, Mann O, Kleinhans H, Schneider C, Knoefel WT, Yekebas E, et al. · Annals of Surgery

Record details
Authors
Strate T, Mann O, Kleinhans H, Schneider C, Knoefel WT, Yekebas E, et al.
Journal
Annals of Surgery
Year
2003
Species / model
Rodent
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Journal Article
DOI
10.1097/01.sla.0000094442.12395.98
PMID
14578741
Original citation
Systemic intravenous infusion of bovine hemoglobin significantly reduces microcirculatory dysfunction in experimentally induced pancreatitis in the rat. Strate T, Mann O, Kleinhans H, Schneider C, Knoefel WT, Yekebas E, Standl T, Bloechle C, Izbicki JR. Ann Surg. 2003 Nov;238(5):765-71. PMID: 14578741 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles
2003Human · In vitro / laboratory

The Effect of the Bovine Hemoglobin Oxygen Therapeutic HBOC-201 on Human Neutrophil Activation In Vitro

Ortegon DP, Dixon PS, Crow KK, Mueller DL, Kerby JD · Journal of Trauma

Record details
Authors
Ortegon DP, Dixon PS, Crow KK, Mueller DL, Kerby JD
Journal
Journal of Trauma
Year
2003
Species / model
Human, In vitro / laboratory
Author institutions
University of Texas Health Science Center at San Antonio
Evidence type
Human clinical evidence
DOI
10.1097/01.ta.0000085722.52921.6d
PMID
14566134
Original citation
The effect of the bovine hemoglobin oxygen therapeutic HBOC-201 on human neutrophil activation in vitro. Ortegon DP, Dixon PS, Crow KK, Mueller DL, Kerby JD. J Trauma. 2003 Oct;55(4):755-60; discussion 760-1. PMID: 14566134 [PubMed - indexed for MEDLINE] Similar articles
2003

The pharmacology of tissue oxygenation by Biopure's hemoglobin-based oxygen carrier, Hemopure (HBOC-201)

Pearce LB, Gawryl MS · Adv Exp Med Biol

Record details
Authors
Pearce LB, Gawryl MS
Journal
Adv Exp Med Biol
Year
2003
Author institutions
Biopure Corporation
Evidence type
Preclinical evidence supporting human development
DOI
10.1007/978-1-4615-0075-9_25
PMID
14562723
Original citation
The pharmacology of tissue oxygenation by biopure's hemoglobin-based oxygen carrier, Hemopure (HBOC-201). Pearce LB, Gawryl MS. Adv Exp Med Biol. 2003;530:261-70. PMID: 14562723 [PubMed - indexed for MEDLINE] Similar articles
2003Human

The use of haemoglobin glutamer-250 (HBOC-201) as an oxygen bridge in patients with acute anaemia associated with surgical blood loss

Levy JH · Expert Opinion on Biological Therapy

Record details
Authors
Levy JH
Journal
Expert Opinion on Biological Therapy
Year
2003
Species / model
Human
Author institutions
Emory University
Evidence type
Reviews, clinical context & policy
DOI
10.1517/14712598.3.3.509
PMID
12783619
Original citation
The use of haemoglobin glutamer-250 (HBOC-201) as an oxygen bridge in patients with acute anaemia associated with surgical blood loss. Levy JH. Expert Opin Biol Ther. 2003 Jun;3(3):509-17. Review. Erratum in: Expert Opin Biol Ther. 2003 Sep;3(6):1017. PMID: 12783619 [PubMed - indexed for MEDLINE] Similar articles
2002

Effects of hemoglobin glutamer-250 (bovine) (HBOC-201, Hemopure) on coagulation testing

Jahr JS, Lurie F, Gosselin R, Lin JS, Wong L, Owings JT, Larkin E · American Journal of Therapeutics

Record details
Authors
Jahr JS, Lurie F, Gosselin R, Lin JS, Wong L, Owings JT, Larkin E
Journal
American Journal of Therapeutics
Year
2002
Evidence type
Preclinical animal
PMID
12237736
Original citation
Effects of hemoglobin glutamer-250 (bovine) (HBOC-201, Hemopure) on coagulation testing. Jahr JS, Lurie F, Gosselin R, Lin JS, Wong L, Owings JT, Larkin E. Am J Ther. 2002 Sep-Oct;9(5):431-6. PMID: 12237736 [PubMed - indexed for MEDLINE] Similar articles
2002

Extracorporeal membrane oxygenation in piglets using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201)

York GB, DiGeronimo RJ, Wilson BJ, Cofer BR, Breuer CK, Josephs JD, Smith DL, Sorrells DL · J Pediatr Surg

Record details
Authors
York GB, DiGeronimo RJ, Wilson BJ, Cofer BR, Breuer CK, Josephs JD, Smith DL, Sorrells DL
Journal
J Pediatr Surg
Year
2002
Evidence type
Preclinical evidence supporting human development
PMID
12378440
Original citation
Extracorporeal membrane oxygenation in piglets using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201). York GB, DiGeronimo RJ, Wilson BJ, Cofer BR, Breuer CK, Josephs JD, Smith DL, Sorrells DL. J Pediatr Surg. 2002 Oct;37(10):1387-92. PMID: 12378440 [PubMed - indexed for MEDLINE] Similar articles
2002Porcine (Pig)

HBOC-201 improves survival in a swine model of hemorrhagic shock and liver injury

Katz LM, Manning JE, McCurdy S, Pearce LB, Gawryl MS, Baker CC · Resuscitation

Record details
Authors
Katz LM, Manning JE, McCurdy S, Pearce LB, Gawryl MS, Baker CC
Journal
Resuscitation
Year
2002
Species / model
Porcine (Pig)
Author institutions
University of North Carolina
Evidence type
Comparative Study; Journal Article
DOI
10.1016/s0300-9572(02)00053-9
PMID
12104112
Original citation
HBOC-201 improves survival in a swine model of hemorrhagic shock and liver injury. Katz LM, Manning JE, McCurdy S, Pearce LB, Gawryl MS, Wang Y, Brown C; Carolina Resuscitation Research Group. Resuscitation. 2002 Jul;54(1):77-87. PMID: 12104112 [PubMed - indexed for MEDLINE] Similar articles
2002

Oxyglobin: a transfusion solution? Hohenhaus AE

Record details
Year
2002
Evidence type
Veterinary clinical / research
DOI
10.1111/j.1939-1676.2002.tb01255.x
PMID
12141299
Original citation
Oxyglobin: a transfusion solution? Hohenhaus AE. J Vet Intern Med. 2002 Jul-Aug;16(4):394-5. No abstract available. PMID: 12141299 [PubMed - indexed for MEDLINE] Free Article Similar articles
2002Human

Polymerized bovine hemoglobin solution as a replacement for allogeneic red blood cell transfusion after cardiac surgery: Results of a randomized, double-blind trial

Levy JH, Goodnough LT, Greilich PE, Parr GV, Stewart RW, Gratz I, et al. · The Journal of Thoracic and Cardiovascular Surgery

Record details
Authors
Levy JH, Goodnough LT, Greilich PE, Parr GV, Stewart RW, Gratz I, et al.
Journal
The Journal of Thoracic and Cardiovascular Surgery
Year
2002
Species / model
Human
Author institutions
Emory University
Evidence type
Human clinical evidence
DOI
10.1067/mtc.2002.121505
PMID
12091806
Original citation
Polymerized bovine hemoglobin solution as a replacement for allogeneic red blood cell transfusion after cardiac surgery: results of a randomized, double-blind trial. Levy JH, Goodnough LT, Greilich PE, Parr GV, Stewart RW, Gratz I, Wahr J, Williams J, Comunale ME, Doblar D, Silvay G, Cohen M, Jahr JS, Vlahakes GJ. J Thorac Cardiovasc Surg. 2002 Jul;124(1):35-42. PMID: 12091806 [PubMed - indexed for MEDLINE] Free Article Similar articles
2002

Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine

Lee SK, Morabito D, Hemphill JC, Erickson V, Holcroft JJ, Derugin N, Knudson MM, Manley GT · Acad Emerg Med

Record details
Authors
Lee SK, Morabito D, Hemphill JC, Erickson V, Holcroft JJ, Derugin N, Knudson MM, Manley GT
Journal
Acad Emerg Med
Year
2002
Evidence type
Preclinical evidence supporting human development
PMID
12359531
Original citation
Small-volume resuscitation with HBOC-201: effects on cardiovascular parameters and brain tissue oxygen tension in an out-of-hospital model of hemorrhage in swine. Lee SK, Morabito D, Hemphill JC, Erickson V, Holcroft JJ, Derugin N, Knudson MM, Manley GT. Acad Emerg Med. 2002 Oct;9(10):969-76. PMID: 12359531 [PubMed - indexed for MEDLINE] Free Article Similar articles
2002Canine (Dog) · In vitro / laboratory

The HemoCue, a point of care B-hemoglobin photometer, measures hemoglobin concentrations accurately when mixed in vitro with canine plasma and three hemoglobin-based oxygen carriers (HBOC)

Jahr JS, Lurie F, Driessen B, Davis JA, Gosselin R, Gunther RA · Canadian Journal of Anesthesia

Record details
Authors
Jahr JS, Lurie F, Driessen B, Davis JA, Gosselin R, Gunther RA
Journal
Canadian Journal of Anesthesia
Year
2002
Species / model
Canine (Dog), In vitro / laboratory
Author institutions
University of California, Los Angeles
Evidence type
Journal Article
DOI
10.1007/bf03020522
PMID
11861341
Original citation
The HemoCue, a point of care B-hemoglobin photometer, measures hemoglobin concentrations accurately when mixed in vitro with canine plasma and three hemoglobin-based oxygen carriers (HBOC). Jahr JS, Lurie F, Driessen B, Davis JA, Gosselin R, Gunther RA. Can J Anaesth. 2002 Mar;49(3):243-8. PMID: 11861341 [PubMed - indexed for MEDLINE] Similar articles
2002Canine (Dog) · In vitro / laboratory

The Novel HemoCue Plasma/Low Hemoglobin System Accurately Measures Small Concentrations of Three Different Hemoglobin-Based Oxygen Carriers in Plasma

Lurie F, Jahr JS, Driessen B · Anesthesia & Analgesia

Record details
Authors
Lurie F, Jahr JS, Driessen B
Journal
Anesthesia & Analgesia
Year
2002
Species / model
Canine (Dog), In vitro / laboratory
Author institutions
University of Hawaii
Evidence type
Comparative Study; Research Support, Non-U.S. Gov't; Evaluation Study; Journal Article
DOI
10.1097/00000539-200210000-00014
PMID
12351259
Original citation
The novel HemoCu plasma/low hemoglobin system accurately measures small concentrations of three different hemoglobin-based oxygen carriers in plasma: hemoglobin glutamer-200 (bovine) (Oxyglobin), hemoglobin glutamer-250 (bovine) (Hemopure), and hemoglobin-Raffimer (Hemolink). Lurie F, Jahr JS, Driessen B. Anesth Analg. 2002 Oct;95(4):870-3, table of contents. PMID: 12351259 [PubMed - indexed for MEDLINE] Similar articles

Manually matched shortened supplied title to full indexed title; authors, year and article identity agree.

2002Rodent · In vitro / laboratory

The Polymerized Bovine Hemoglobin-Based Oxygen-Carrying Solution (HBOC-201) Is Not Toxic to Neural Cells in Culture

Ortegon DP, Davis MR, Dixon PS, Smith DL, Josephs JD, Mueller DL, et al. · Journal of Trauma

Record details
Authors
Ortegon DP, Davis MR, Dixon PS, Smith DL, Josephs JD, Mueller DL, et al.
Journal
Journal of Trauma
Year
2002
Species / model
Rodent, In vitro / laboratory
Author institutions
University of Texas Health Science Center at San Antonio
Evidence type
In vitro & analytical evidence
DOI
10.1097/00005373-200212000-00007
PMID
12478030
Original citation
The polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) is not toxic to neural cells in culture. Ortegon DP, Davis MR, Dixon PS, Smith DL, Josephs JD, Mueller DL, Jenkins DH, Kerby JD. J Trauma. 2002 Dec;53(6):1068-72. PMID: 12478030 [PubMed - indexed for MEDLINE] Similar articles
2002Human

The Use of Bovine Hemoglobin Glutamer-250 (Hemopure) in Surgical Patients: Results of a Multicenter, Randomized, Single-Blinded Trial

Sprung J, Kindscher JD, Wahr JA, Levy JH, Monk TG, Moritz MW, et al. · Anesthesia & Analgesia

Record details
Authors
Sprung J, Kindscher JD, Wahr JA, Levy JH, Monk TG, Moritz MW, et al.
Journal
Anesthesia & Analgesia
Year
2002
Species / model
Human
Author institutions
Cleveland Clinic
Evidence type
Human clinical evidence
DOI
10.1097/00000539-200204000-00006
PMID
11916776
Original citation
The use of bovine hemoglobin glutamer-250 (Hemopure) in surgical patients: results of a multicenter, randomized, single-blinded trial. Sprung J, Kindscher JD, Wahr JA, Levy JH, Monk TG, Moritz MW, O'Hara PJ. Anesth Analg. 2002 Apr;94(4):799-808, table of contents. PMID: 11916776 [PubMed - indexed for MEDLINE] Similar articles
2002Equine (Horse)

The use of ultrapurified bovine hemoglobin solution in the treatment of two cases of presumed red maple toxicosis in a miniature horse and a pony

Vin R, Bedenice D, Rentko VT, Paradis MR · Journal of Veterinary Emergency and Critical Care

Record details
Authors
Vin R, Bedenice D, Rentko VT, Paradis MR
Journal
Journal of Veterinary Emergency and Critical Care
Year
2002
Species / model
Equine (Horse)
Author institutions
Biopure Corporation, Tufts University
Evidence type
Veterinary clinical / research
DOI
10.1046/j.1435-6935.2002.00013.x
Original citation
Vin R, Bedenice D, Rentko VT and Paradis, MR. The use of ultrapurified bovine hemoglobin solution in the treatment of two cases of presumed red maple toxicosis in a miniature horse and a pony. J Vet Emerg Crit Care. 2002;(12):169–175

Title, authors, journal and original publication year checked against the publisher and DOI registration. Not represented as a PubMed-indexed record.

2002Feline (Cat)

Use of a hemoglobin-based oxygen-carrying solution in cats: 72 cases (1998-2000)

Gibson GR, Callan MB, Hoffman V, Giger U · Journal of the American Veterinary Medical Association

Record details
Authors
Gibson GR, Callan MB, Hoffman V, Giger U
Journal
Journal of the American Veterinary Medical Association
Year
2002
Species / model
Feline (Cat)
Author institutions
University of Pennsylvania
Evidence type
Journal Article
DOI
10.2460/javma.2002.221.96
PMID
12420832
Original citation
Gibson GR, Callan MB, Hoffman V, Giger U. Use of a hemoglobin-based oxygen-carrying solution in cats: 72 cases ( 1998-2000). J Am Vet Med Assoc. 2002 Jul 1;221(1):96-102.
2001Canine (Dog)

Absence of immunopathology associated with repeated IV administration of bovine Hb-based oxygen carrier in dogs

Hamilton RG, Kelly N, Gawryl MS, Rentko VT · Transfusion

Record details
Authors
Hamilton RG, Kelly N, Gawryl MS, Rentko VT
Journal
Transfusion
Year
2001
Species / model
Canine (Dog)
Author institutions
Johns Hopkins University
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.1046/j.1537-2995.2001.41020219.x
PMID
11239226
Original citation
Absence of immunopathology associated with repeated IV administration of bovine Hb-based oxygen carrier in dogs. Hamilton RG, Kelly N, Gawryl MS, Rentko VT. Transfusion. 2001 Feb;41(2):219-25. PMID: 11239226 [PubMed - indexed for MEDLINE] Similar articles
2001

Bovine hemoglobin (HBOC-201) restores tissue oxygen tension during peripheral and coronary artery stenosis under extended hemodilution

Horn EP, Burmeister MA · Anasthesiol Intensivmed Notfallmed Schmerzther

Record details
Authors
Horn EP, Burmeister MA
Journal
Anasthesiol Intensivmed Notfallmed Schmerzther
Year
2001
Evidence type
Preclinical evidence supporting human development
PMID
11753715
Original citation
Bovine hemoglobin (HBOC-201) restores tissue oxygen tension during peripheral and coronary artery stenosis under extended hemodilution. Horn EP, Burmeister MA. Anasthesiol Intensivmed Notfallmed Schmerzther. 2001 Nov;36 Suppl 2:S117-8. No abstract available. PMID: 11753715 [PubMed - indexed for MEDLINE] Similar articles
2001

Clinical update: Hemopure(r) - a room temperature stable hemoglobin oxygen carrier

Jacobs E · Anasthesiol Intensivmed Notfallmed Schmerzther

Record details
Authors
Jacobs E
Journal
Anasthesiol Intensivmed Notfallmed Schmerzther
Year
2001
Evidence type
Preclinical animal
PMID
11753717
Original citation
Clinical update: Hemopure(r) - a room temperature stable hemoglobin oxygen carrier. Jacobs E. Anasthesiol Intensivmed Notfallmed Schmerzther. 2001 Nov;36 Suppl 2:S121-2. No abstract available. PMID: 11753717 [PubMed - indexed for MEDLINE] Similar articles
2001Canine (Dog) · Ovine (Sheep)

Effects of haemoglobin-based oxygen carrier hemoglobin glutamer-200 (bovine) on intestinal perfusion and oxygenation in a canine hypovolaemia model

Driessen B, Jahr JS, Lurie F, Griffey SM, Gunther RA · British Journal of Anaesthesia

Record details
Authors
Driessen B, Jahr JS, Lurie F, Griffey SM, Gunther RA
Journal
British Journal of Anaesthesia
Year
2001
Species / model
Canine (Dog), Ovine (Sheep)
Author institutions
University of Pennsylvania
Evidence type
Journal Article
DOI
10.1093/bja/86.5.683
PMID
11575346
Original citation
Effects of haemoglobin-based oxygen carrier hemoglobin glutamer-200 (bovine) on intestinal perfusion and oxygenation in a canine hypovolaemia model. Driessen B, Jahr JS, Lurie F, Griffey SM, Gunther RA. Br J Anaesth. 2001 May;86(5):683-92. Erratum in: Br J Anaesth 2001 Jul;87(1):164. Br J Anaesth 2001 Aug;87(2):329. PMID: 11575346 [PubMed - indexed for MEDLINE] Free Article Similar articles

Distinct British Journal of Anaesthesia full paper, PMID 11575346. It is related to but must not replace the separate Veterinary Anaesthesia and Analgesia record PMID 28404246.

2001Canine (Dog)

Effects of the haemoglobin-based oxygen carrier Hemoglobin glutamer-200 (bovine) on intestinal perfusion and oxygenation in a canine hypovolaemia model

Driessen B, Jahr JS, Lurie F, Gunther RA · Veterinary Anaesthesia and Analgesia

Record details
Authors
Driessen B, Jahr JS, Lurie F, Gunther RA
Journal
Veterinary Anaesthesia and Analgesia
Year
2001
Species / model
Canine (Dog)
Author institutions
University of California, Davis, University of Pennsylvania
Evidence type
Journal Article
DOI
10.1111/j.1467-2987.2001.064-2.x
PMID
28404246
2001Porcine (Pig)

Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism

McNeil CJ, Smith LD, Jenkins LD, York MG, Josephs MJ · Journal of Trauma

Record details
Authors
McNeil CJ, Smith LD, Jenkins LD, York MG, Josephs MJ
Journal
Journal of Trauma
Year
2001
Species / model
Porcine (Pig)
Author institutions
Wilford Hall Medical Center
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/00005373-200106000-00015
PMID
11426122
Original citation
Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen- carrying solution (HBOC-201) leads to reversal of anaerobic metabolism. McNeil CJ, Smith LD, Jenkins LD, York MG, Josephs MJ. J Trauma. 2001 Jun;50(6):1063-75. PMID: 11426122 [PubMed - indexed for MEDLINE] Similar articles
2001Canine (Dog)

Inadequacy of low-volume resuscitation with hemoglobin-based oxygen carrier hemoglobin glutamer-200 (bovine) in canine hypovolemia

Driessen B, Jahr JS, Lurie F, Gunther RA · Journal of Veterinary Pharmacology and Therapeutics

Record details
Authors
Driessen B, Jahr JS, Lurie F, Gunther RA
Journal
Journal of Veterinary Pharmacology and Therapeutics
Year
2001
Species / model
Canine (Dog)
Author institutions
University of Pennsylvania
Evidence type
Clinical Trial; Journal Article
DOI
10.1046/j.1365-2885.2001.00307.x
PMID
11348488
Original citation
Inadequacy of low-volume resuscitation with hemoglobin-based oxygen carrier hemoglobin glutamer-200 (bovine) in canine hypovolemia. Driessen B, Jahr JS, Lurie F, Gunther RA. J Vet Pharmacol Ther. 2001 Feb;24(1):61-71. PMID: 11348488 [PubMed - indexed for MEDLINE] Similar articles
2001

Oxygen saturation measurements in canine blood containing hemoglobin glutamer-200 (Bovine): in vitro validation of the NOVA CO-Oximeter

Jahr JS, Driessen B, Lurie F, Tang Z, Louie RF, Kost G · Vet Clin Pathol

Record details
Authors
Jahr JS, Driessen B, Lurie F, Tang Z, Louie RF, Kost G
Journal
Vet Clin Pathol
Year
2001
Evidence type
Veterinary clinical / research
PMID
12024330
Original citation
Oxygen saturation measurements in canine blood containing hemoglobin glutamer-200 (Bovine): in vitro validation of the NOVA CO-Oximeter. Jahr JS, Driessen B, Lurie F, Tang Z, Louie RF, Kost G. Vet Clin Pathol. 2001;30(1):39-45. PMID: 12024330 [PubMed - as supplied by publisher] Similar articles
2001Other animal

Polymerized bovine hemoglobin (Oxyglobin Solution) administration in two river otters (Lutra canadensis)

McEwen M-M, Moon-Massat PF, Butler EC, Kollias GV · Veterinary Anaesthesia and Analgesia

Record details
Authors
McEwen M-M, Moon-Massat PF, Butler EC, Kollias GV
Journal
Veterinary Anaesthesia and Analgesia
Year
2001
Species / model
Other animal
Author institutions
Cornell University
Evidence type
Journal Article
DOI
10.1046/j.1467-2987.2001.00055.x
PMID
28404257
Original citation
McEwen MM, Moon-Massat PF, Butler EC, Kollias GV. Polymerized bovine hemoglobin (Oxyglobin Solution) administration in two river otters (Lutra canadensis). Vet Anaesth Analg. 2001 Oct;28(4):214-219. doi: 10.1046/j.1467-2987.2001.00055.x. Epub 2016 Nov 15. PMID:28404257
2001Equine (Horse)

Polymerized Hemoglobin Therapy in a Foal with Neonatal Isoerythrolysis

Perkins GA, Divers TJ · Journal of Veterinary Emergency and Critical Care

Record details
Authors
Perkins GA, Divers TJ
Journal
Journal of Veterinary Emergency and Critical Care
Year
2001
Species / model
Equine (Horse)
Author institutions
Cornell University
Evidence type
Preclinical animal
DOI
10.1111/j.1476-4431.2001.tb00079.x
Original citation
Perkins, GA and Divers, T.J, Polymerized Hemoglobin Therapy in a Foal with Neonatal Isoerythrolysis. J Vet Emerg Crit Car. 2001;(11):141–146.

Title, authors, journal and original publication year checked against the publisher and DOI registration. Not represented as a PubMed-indexed record. The issue year is 2001; the later online posting date is not the original publication year.

2001Canine (Dog)

The Effects of Hemoglobin Glutamer-200 (Bovine) on the Microcirculation in a Canine Hypovolemia Model: A Noninvasive Computer-Assisted Intravital Microscopy Study

Cheung AT, Jahr JS, Driessen B, Duong PL, Chan MS, Lurie F, Golkaryeh MS, Kullar RK, Gunther RA · Anesthesia & Analgesia

Record details
Authors
Cheung AT, Jahr JS, Driessen B, Duong PL, Chan MS, Lurie F, Golkaryeh MS, Kullar RK, Gunther RA
Journal
Anesthesia & Analgesia
Year
2001
Species / model
Canine (Dog)
Author institutions
University of California, Davis
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.1097/00000539-200110000-00007
PMID
11574342
Original citation
The effects of hemoglobin glutamer-200 (bovine) on the microcirculation in a canine hypovolemia model: a noninvasive computer-assisted intravital microscopy study. Cheung AT, Jahr JS, Driessen B, Duong PL, Chan MS, Lurie F, Golkaryeh MS, Kullar RK, Gunther RA. Anesth Analg. 2001 Oct;93(4):832-8. PMID: 11574342 [PubMed - indexed for MEDLINE] Similar articles
2001Rodent · Human

The potential of HBOC in acute pancreatitis

Strate T, Mann O, Standl T, Izbicki JR, Knoefel WT · Anasthesiol Intensivmed Notfallmed Schmerzther

Record details
Authors
Strate T, Mann O, Standl T, Izbicki JR, Knoefel WT
Journal
Anasthesiol Intensivmed Notfallmed Schmerzther
Year
2001
Species / model
Rodent, Human
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Journal Article
DOI
10.1055/s-2001-18187
PMID
11753716
Original citation
Strate T, Mann O, Standl T, Izbicki JR, Knoefel WT. The potential of HBOC in acute pancreatitis. Anasthesiol Intensivmed Notfallmed Schmerzther. 2001 Nov;36 Suppl 2:S119-20. No abstract available.
2001Human

The successful use of hemoglobin-based oxygen carrier as a primary blood substitute during abdominal aneurysm repair with large blood loss

Sprung J, Popp H, O'Hara P, Woletz J · Anesthesia & Analgesia

Record details
Authors
Sprung J, Popp H, O'Hara P, Woletz J
Journal
Anesthesia & Analgesia
Year
2001
Species / model
Human
Author institutions
Mayo Clinic
Evidence type
Human clinical evidence
DOI
10.1097/00000539-200106000-00010
PMID
11375814
Original citation
The successful use of hemoglobin-based oxygen carrier as a primary blood substitute during abdominal aneurysm repair with large blood loss. Sprung J, Popp H, O'Hara P, Woletz J. Anesth Analg. 2001 Jun;92(6):1413-5. No abstract available. PMID: 11375814 [PubMed - indexed for MEDLINE] Similar articles
2000Porcine (Pig)

Bovine Hemoglobin-Based Oxygen Carrier (HBOC-201) For Resuscitation of Uncontrolled, Exsanguinating Liver Injury in Swine

Manning JE, Katz LM, Brownstein MR, Pearce LB, Gawryl MS, Baker CC · Shock

Record details
Authors
Manning JE, Katz LM, Brownstein MR, Pearce LB, Gawryl MS, Baker CC
Journal
Shock
Year
2000
Species / model
Porcine (Pig)
Author institutions
University of North Carolina
Evidence type
Preclinical evidence supporting human development
DOI
10.1097/00024382-200013020-00010
PMID
10670846
Original citation
Bovine hemoglobin-based oxygen carrier (HBOC-201) for resuscitation of uncontrolled, exsanguinating liver injury in swine. Carolina Resuscitation Research Group. Manning JE, Katz LM, Brownstein MR, Pearce LB, Gawryl MS, Baker CC. Shock. 2000 Feb;13(2):152-9. PMID: 10670846 [PubMed - indexed for MEDLINE] Similar articles
2000Human · In vitro / laboratory

Effects of a Hemoglobin-Based Oxygen Carrier (HBOC-201) on Coagulation Testing

Jahr JS, Lurie F, Gosselin R, Lin JS, Wong L, Larkin E · Clinical Laboratory Science

Record details
Authors
Jahr JS, Lurie F, Gosselin R, Lin JS, Wong L, Larkin E
Journal
Clinical Laboratory Science
Year
2000
Species / model
Human, In vitro / laboratory
Author institutions
University of California, Davis
Evidence type
Journal Article
PMID
11586506
Original citation
Effects of a hemoglobin-based oxygen carrier (HBOC-201) on coagulation testing. Jahr JS, Lurie F, Gosselin R, Lin JS, Wong L, Larkin E. Clin Lab Sci. 2000 Fall;13(4):210-4. PMID: 11586506 [PubMed - indexed for MEDLINE] Similar articles
2000Canine (Dog)

The Effects of a Hemoglobin-Based Oxygen Carrier (HBOC-301) on Left Ventricular Systolic Function in Anesthetized Dogs

Muir WW 3rd, de Morais HS, Constable PD · Veterinary Surgery

Record details
Authors
Muir WW 3rd, de Morais HS, Constable PD
Journal
Veterinary Surgery
Year
2000
Species / model
Canine (Dog)
Author institutions
The Ohio State University
Evidence type
Journal Article
DOI
10.1053/jvet.2000.9137
PMID
10999460
Original citation
Muir WW 3rd, de Morais HS, Constable PD. The effects of a hemoglobin-based oxygen carrier (HBOC-301) on left ventricular systolic function in anesthetized dogs. Vet Surg. 2000 Sep-Oct;29(5):449-55. PMID:10999460
2000Human

The reduction of the allogenic transfusion requirement in aortic surgery with a hemoglobin-based solution

LaMuraglia GM, O'Hara PJ, Baker WH, Naslund TC, Norris EJ, Li J, Vandermeersch E · Journal of Vascular Surgery

Record details
Authors
LaMuraglia GM, O'Hara PJ, Baker WH, Naslund TC, Norris EJ, Li J, Vandermeersch E
Journal
Journal of Vascular Surgery
Year
2000
Species / model
Human
Author institutions
Harvard Medical School, Massachusetts General Hospital
Evidence type
Human clinical evidence
DOI
10.1016/s0741-5214(00)90161-7
PMID
10664499
Original citation
The reduction of the allogenic transfusion requirement in aortic surgery with a hemoglobin-based solution. LaMuraglia GM, O'Hara PJ, Baker WH, Naslund TC, Norris EJ, Li J, Vandermeersch E. J Vasc Surg. 2000 Feb;31(2):299-308. PMID: 10664499 [PubMed - indexed for MEDLINE] Free Article Similar articles
2000Human

Transfusions of polymerized bovine hemoglobin in a patient with severe autoimmune hemolytic anemia

Mullon J, Giacoppe G, Clagett C, McCune D, Dillard T · New England Journal of Medicine

Record details
Authors
Mullon J, Giacoppe G, Clagett C, McCune D, Dillard T
Journal
New England Journal of Medicine
Year
2000
Species / model
Human
Author institutions
Madigan Army Medical Center
Evidence type
Human clinical evidence
DOI
10.1056/nejm200006013422204
PMID
10836875
Original citation
Transfusions of polymerized bovine hemoglobin in a patient with severe autoimmune hemolytic anemia. Mullon J, Giacoppe G, Clagett C, McCune D, Dillard T. N Engl J Med. 2000 Jun 1;342(22):1638-43. No abstract available. PMID: 10836875 [PubMed - indexed for MEDLINE] Free Article Similar articles
1999Human · In vitro / laboratory

Effect of the Hemoglobin-Based Oxygen Carrier HBOC-201 on Laboratory Instrumentation: Cobas Integra, Chiron Blood Gas Analyzer 840, Sysmex SE-9000 and BCT

Wolthuis A, Peek D, Scholten R, Moreira P, Gawryl M, Clark T, Westerhuis L · Clinical Chemistry and Laboratory Medicine

Record details
Authors
Wolthuis A, Peek D, Scholten R, Moreira P, Gawryl M, Clark T, Westerhuis L
Journal
Clinical Chemistry and Laboratory Medicine
Year
1999
Species / model
Human, In vitro / laboratory
Author institutions
Atrium Medisch Centrum Heerlen
Evidence type
Journal Article
DOI
10.1515/cclm.1999.011
PMID
10094382
Original citation
Effect of the hemoglobin-based oxygen carrier HBOC-201 on laboratory instrumentation: cobas integra, chiron blood gas analyzer 840, Sysmex SE-9000 and BCT. Wolthuis A, Peek D, Scholten R, Moreira P, Gawryl M, Clark T, Westerhuis L. Clin Chem Lab Med. 1999 Jan;37(1):71-6. PMID: 10094382 [PubMed - indexed for MEDLINE] Similar articles
1999Canine (Dog)

Radiographic, Biomechanical, and Pathologic Effects of Hemoglobin Glutamer-200 in Dogs Undergoing Cemented Total Hip Arthroplasty

Braden TD, Tvedten HW, DeCamp CE, Turner TM, Hughes GS, Rentko VT · American Journal of Veterinary Research

Record details
Authors
Braden TD, Tvedten HW, DeCamp CE, Turner TM, Hughes GS, Rentko VT
Journal
American Journal of Veterinary Research
Year
1999
Species / model
Canine (Dog)
Author institutions
Michigan State University
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.2460/ajvr.1999.60.11.1337
PMID
10566804
Original citation
Radiographic, biomechanical, and pathologic effects of hemoglobin glutamer-200 in dogs undergoing cemented total hip arthroplasty. Braden TD, Tvedten HW, DeCamp CE, Turner TM, Hughes GS, Rentko VT. Am J Vet Res. 1999 Nov;60(11):1337-40. PMID: 10566804 [PubMed - indexed for MEDLINE] Similar articles
1999Human

Transfusion medicine. First of two parts--blood transfusion

Goodnough LT, Brecher ME, Kanter MH, AuBuchon JP · New England Journal of Medicine

Record details
Authors
Goodnough LT, Brecher ME, Kanter MH, AuBuchon JP
Journal
New England Journal of Medicine
Year
1999
Species / model
Human
Author institutions
Washington University in St. Louis
Evidence type
Pending full-text classification
DOI
10.1056/nejm199902113400606
PMID
9971869
Original citation
Goodnough LT, Brecher ME, Kanter MH, AuBuchon JP. Transfusion medicine. First of two parts--blood transfusion. N Engl J Med. 1999 Feb 11;340(6):438-47.
1998

[Bovine hemoglobin. HBOC-201 causes a reduction of the oxygen partial pressure in poststenotic skeletal muscle]

Horn EP, Standl T, Wilhelm S, Jacobs EE, Freitag U, Freitag M, Schulte am Esch J · Anaesthesist

Record details
Authors
Horn EP, Standl T, Wilhelm S, Jacobs EE, Freitag U, Freitag M, Schulte am Esch J
Journal
Anaesthesist
Year
1998
Evidence type
Preclinical animal
PMID
9530461
Original citation
[Bovine hemoglobin. HBOC-201 causes a reduction of the oxygen partial pressure in poststenotic skeletal muscle]. Horn EP, Standl T, Wilhelm S, Jacobs EE, Freitag U, Freitag M, Schulte am Esch J. Anaesthesist. 1998 Feb;47(2):116-23. German. PMID: 9530461 [PubMed - indexed for MEDLINE] Similar articles
1998Human

The effects of increased doses of bovine hemoglobin on hemodynamics and oxygen transport in patients undergoing preoperative hemodilution for elective abdominal aortic surgery

Kasper SM, Grüne F, Walter M, Amr N, Erasmi H, Buzello W · Anesthesia & Analgesia

Record details
Authors
Kasper SM, Grüne F, Walter M, Amr N, Erasmi H, Buzello W
Journal
Anesthesia & Analgesia
Year
1998
Species / model
Human
Author institutions
University of Cologne
Evidence type
Human clinical evidence
DOI
10.1097/00000539-199808000-00009
PMID
9706917
Original citation
The effects of increased doses of bovine hemoglobin on hemodynamics and oxygen transport in patients undergoing preoperative hemodilution for elective abdominal aortic surgery. Kasper SM, Grüne F, Walter M, Amr N, Erasmi H, Buzello W. Anesth Analg. 1998 Aug;87(2):284-91. PMID: 9706917 [PubMed - indexed for MEDLINE] Similar articles
1997Human

A phase I/II study of polymerized bovine hemoglobin in adult patients with sickle cell disease not in crisis at the time of study

Gonzalez P, Hackney AC, Jones S, Strayhorn D, Hoffman EB, Hughes G, Jacobs EE, Orringer EP · Journal of Investigative Medicine

Record details
Authors
Gonzalez P, Hackney AC, Jones S, Strayhorn D, Hoffman EB, Hughes G, Jacobs EE, Orringer EP
Journal
Journal of Investigative Medicine
Year
1997
Species / model
Human
Author institutions
University of North Carolina
Evidence type
Human clinical evidence
PMID
9249998
Original citation
A phase I/II study of polymerized bovine hemoglobin in adult patients with sickle cell disease not in crisis at the time of study. Gonzalez P, Hackney AC, Jones S, Strayhorn D, Hoffman EB, Hughes G, Jacobs EE, Orringer EP. J Investig Med. 1997 Jun;45(5):258-64. PMID: 9249998 [PubMed - indexed for MEDLINE] Similar articles
1997Human · In vitro / laboratory

Effect of Hemoglobin-Based Oxygen Carrier-201 on Common Chemistry Laboratory Procedures

Sarkozi L, Jacobs E, Clark T, Gawryl MS, Simson E · Clinical Chemistry

Record details
Authors
Sarkozi L, Jacobs E, Clark T, Gawryl MS, Simson E
Journal
Clinical Chemistry
Year
1997
Species / model
Human, In vitro / laboratory
Author institutions
Mount Sinai School of Medicine
Evidence type
Journal Article
DOI
10.1093/clinchem/43.9.1792a
PMID
9299983
Original citation
Effect of hemoglobin-based oxygen carrier-201 on common chemistry laboratory procedures. Sarkozi L, Jacobs E, Clark T, Gawryl MS, Simson E. Clin Chem. 1997 Sep;43(9):1792-4. No abstract available. PMID: 9299983 [PubMed - indexed for MEDLINE] Free Article Similar articles
1997Human · In vitro / laboratory

Effect of Hemopure on Prothrombin Time and Activated Partial Thromboplastin Time on Seven Coagulation Analyzers

Moreira PL, Lansden CC, Clark TL, Gawryl MS

Record details
Authors
Moreira PL, Lansden CC, Clark TL, Gawryl MS
Journal
Nonclinical
Year
1997
Species / model
Human, In vitro / laboratory
Author institutions
Biopure Corporation
Evidence type
Comparative Study; Journal Article
DOI
10.1093/clinchem/43.9.1792
PMID
9299982
Original citation
Effect of Hemopure on prothrombin time and activated partial thromboplastin time on seven coagulation analyzers. Moreira PL, Lansden CC, Clark TL, Gawryl MS. Clin Chem. 1997 Sep;43(9):1792. No abstract available. PMID: 9299982 [PubMed - indexed for MEDLINE] Free Article Similar articles
1997

Effect of Hemopure on the performance of Ektachem and Hitachi clinical analyzers

Moreira PL, Lansden CC, Clark TL, Gawryl MS · Clinical Chemistry

Record details
Authors
Moreira PL, Lansden CC, Clark TL, Gawryl MS
Journal
Clinical Chemistry
Year
1997
Evidence type
Unclear — verify full text
PMID
9299981
Original citation
Effect of Hemopure on the performance of Ektachem and Hitachi clinical analyzers. Moreira PL, Lansden CC, Clark TL, Gawryl MS. Clin Chem. 1997 Sep;43(9):1790-1. No abstract available. PMID: 9299981 [PubMed - indexed for MEDLINE] Free Article Similar articles
1997Human

The effects of a blood-salvaging device on blood containing a hemoglobin-based oxygen carrier, HBOC-201

Whar JA, Anderson MM, Giacherio DA, Hallock L, Gawryl MS, Lansden C, et al. · Journal of Cardiothoracic and Vascular Anesthesia

Record details
Authors
Whar JA, Anderson MM, Giacherio DA, Hallock L, Gawryl MS, Lansden C, et al.
Journal
Journal of Cardiothoracic and Vascular Anesthesia
Year
1997
Species / model
Human
Author institutions
University of Michigan
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.1016/s1053-0770(97)90244-5
PMID
9058212
Original citation
The effects of a blood-salvaging device on blood containing a hemoglobin-based oxygen carrier, HBOC-201. Wahr JA, Anderson MM, Giacherio DA, Hallock L, Gawryl MS, Lansden C, Tremper KK. J Cardiothorac Vasc Anesth. 1997 Feb;11(1):10-2. PMID: 9058212 [PubMed - indexed for MEDLINE] Similar articles
1996Human

Blood transfusion in orthopaedic operations

Lemos MJ, Healy WL · Journal of Bone and Joint Surgery. American Volume

Record details
Authors
Lemos MJ, Healy WL
Journal
Journal of Bone and Joint Surgery. American Volume
Year
1996
Species / model
Human
Author institutions
Lahey Hitchcock Medical Center
Evidence type
Preclinical evidence supporting human development
DOI
10.2106/00004623-199608000-00019
PMID
8753721
Original citation
Lemos MJ, Healy WL. Blood transfusion in orthopaedic operations. J Bone Joint Surg Am. 1996 Aug;78(8):1260-70.
1996Canine (Dog)

Bovine haemoglobin is more potent than autologous red blood cells in restoring muscular tissue oxygenation after profound isovolaemic haemodilution in dogs

Standl T, Horn P, Wilhelm S, Greim C, Freitag M, Freitag U, Sputtek A, Jacobs E, Schulte am Esch J · Canadian Journal of Anesthesia

Record details
Authors
Standl T, Horn P, Wilhelm S, Greim C, Freitag M, Freitag U, Sputtek A, Jacobs E, Schulte am Esch J
Journal
Canadian Journal of Anesthesia
Year
1996
Species / model
Canine (Dog)
Author institutions
University Medical Center Hamburg-Eppendorf
Evidence type
Journal Article
DOI
10.1007/bf03017957
PMID
8807179
Original citation
Standl T, Horn P, Wilhelm S, Greim C, Freitag M, Freitag U, Sputtek A, Jacobs E, Schulte am Esch J. Bovine haemoglobin is more potent than autologous red blood cells in restoring muscular tissue oxygenation after profound isovolaemic haemodilution in dogs. Can J Anaesth. 1996 Jul;43(7):714-23.
1996Human

Effects of a Hemoglobin-Based Oxygen Carrier (HBOC-201) on Hemodynamics and Oxygen Transport in Patients Undergoing Preoperative Hemodilution for Elective Abdominal Aortic Surgery

Kasper SM, Walter M, Grüne F, Bischoff A, Erasmi H, Buzello W · Anesthesia & Analgesia

Record details
Authors
Kasper SM, Walter M, Grüne F, Bischoff A, Erasmi H, Buzello W
Journal
Anesthesia & Analgesia
Year
1996
Species / model
Human
Author institutions
University of Cologne
Evidence type
Human clinical evidence
DOI
10.1097/00000539-199611000-00006
PMID
8895264
Original citation
Effects of a hemoglobin-based oxygen carrier (HBOC-201) on hemodynamics and oxygen transport in patients undergoing preoperative hemodilution for elective abdominal aortic surgery. Kasper SM, Walter M, Grüne F, Bischoff A, Erasmi H, Buzello W. Anesth Analg. 1996 Nov;83(5):921-7. PMID: 8895264 [PubMed - indexed for MEDLINE] Similar articles
1996Human

Effects of a novel hemoglobin-based oxygen carrier on percent oxygen saturation as determined with arterial blood gas analysis and pulse oximetry

Hughes GS, Francom SF, Antal EJ, Adams WJ, Locker PK, Yancey EP, Jacobs EE · Annals of Emergency Medicine

Record details
Authors
Hughes GS, Francom SF, Antal EJ, Adams WJ, Locker PK, Yancey EP, Jacobs EE
Journal
Annals of Emergency Medicine
Year
1996
Species / model
Human
Author institutions
Upjohn / Pharmacia and Upjohn
Evidence type
Human clinical evidence
DOI
10.1016/s0196-0644(96)70318-9
PMID
8629746
Original citation
Effects of a novel hemoglobin-based oxygen carrier on percent oxygen saturation as determined with arterial blood gas analysis and pulse oximetry. Hughes GS, Francom SF, Antal EJ, Adams WJ, Locker PK, Yancey EP, Jacobs EE. Ann Emerg Med. 1996 Feb;27(2):164-9. PMID: 8629746 [PubMed - indexed for MEDLINE] Similar articles
1996Human

Physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier in humans

Hughes GS Jr, Antal EJ, Locker PK, Francom SF, Adams WJ, Jacobs EE Jr · Critical Care Medicine

Record details
Authors
Hughes GS Jr, Antal EJ, Locker PK, Francom SF, Adams WJ, Jacobs EE Jr
Journal
Critical Care Medicine
Year
1996
Species / model
Human
Author institutions
Upjohn / Pharmacia and Upjohn
Evidence type
Human clinical evidence
DOI
10.1097/00003246-199605000-00006
PMID
8706450
Original citation
Hughes GS Jr, Antal EJ, Locker PK, Francom SF, Adams WJ, Jacobs EE Jr. Physiology and pharmacokinetics of a novel hemoglobin-based oxygen carrier in humans. Crit Care Med. 1996 May;24(5):756-64.
1995Human

Hematologic effects of a novel hemoglobin-based oxygen carrier in normal male and female subjects

Hughes GS, Francome SF, Antal EJ, Adams WJ, Locker PK, Yancey EP, et al. · Journal of Laboratory and Clinical Medicine

Record details
Authors
Hughes GS, Francome SF, Antal EJ, Adams WJ, Locker PK, Yancey EP, et al.
Journal
Journal of Laboratory and Clinical Medicine
Year
1995
Species / model
Human
Author institutions
Upjohn / Pharmacia and Upjohn
Evidence type
Human clinical evidence
PMID
7595029
Original citation
Hematologic effects of a novel hemoglobin-based oxygen carrier in normal male and female subjects. Hughes GS Jr, Francome SF, Antal EJ, Adams WJ, Locker PK, Yancey EP, Jacobs EE Jr. J Lab Clin Med. 1995 Nov;126(5):444-51. PMID: 7595029 [PubMed - indexed for MEDLINE] Similar articles
1995Human

Hemoglobin-based oxygen carrier preserves submaximal exercise capacity in humans

Hughes GS Jr, Yancey EP, Albrecht R, Locker PK, Francom SF, Orringer EP, Antal EJ, Jacobs EE Jr · Clinical Pharmacology & Therapeutics

Record details
Authors
Hughes GS Jr, Yancey EP, Albrecht R, Locker PK, Francom SF, Orringer EP, Antal EJ, Jacobs EE Jr
Journal
Clinical Pharmacology & Therapeutics
Year
1995
Species / model
Human
Author institutions
Upjohn / Pharmacia and Upjohn
Evidence type
Human clinical evidence
DOI
10.1016/0009-9236(95)90057-8
PMID
7586936
Original citation
Hemoglobin-based oxygen carrier preserves submaximal exercise capacity in humans. Hughes GS Jr, Yancey EP, Albrecht R, Locker PK, Francom SF, Orringer EP, Antal EJ, Jacobs EE Jr. Clin Pharmacol Ther. 1995 Oct;58(4):434-43. PMID: 7586936 [PubMed - indexed for MEDLINE] Similar articles
1995Ovine (Sheep)

Limitations of the efficacy of hemoglobin-based oxygen-carrying solutions

Lee R, Neya K, Svizzero TA, Vlahakes GJ · Journal of Applied Physiology

Record details
Authors
Lee R, Neya K, Svizzero TA, Vlahakes GJ
Journal
Journal of Applied Physiology
Year
1995
Species / model
Ovine (Sheep)
Author institutions
Massachusetts General Hospital
Evidence type
Journal Article
DOI
10.1152/jappl.1995.79.1.236
PMID
7559226
Original citation
Lee R, Neya K, Svizzero TA, Vlahakes GJ. Limitations of the efficacy of hemoglobin-based oxygen-carrying solutions. J Appl Physiol (1985). 1995 Jul;79(1):236-42.
1993Equine (Horse)

Use of a bovine hemoglobin preparation in the treatment of cyclic ovarian hemorrhage in a miniature horse

Maxson AD, Giger U, Sweeney CR, Tomasic M, Saik JE, Donawick WJ, Cothran EG

Record details
Authors
Maxson AD, Giger U, Sweeney CR, Tomasic M, Saik JE, Donawick WJ, Cothran EG
Journal
Equine
Year
1993
Species / model
Equine (Horse)
Author institutions
University of Pennsylvania
Evidence type
Journal Article; Case Reports
PMID
8253625
Original citation
Maxson, Abby D., VMD, Urs Giger, PD, Dr Med Vet, Corinne R. Sweeney, DVM, Michael Tomasic, VMD, Judith E. Saik, DVM, William J. Donawick, DVM, and E. Gus Cothran, PhD. "Use of a Bovine Hemoglobin Preparation in the Treatment of Cyclic Ovarian Hemorrhage in a Miniature Horse." Equine 203, no. 9 (November 1, 1993): 1308-311.
1991Canine (Dog)

Purified Hemoglobin used as a blood substitute in the treatment of parasite-induced anemia in dogs

Giger U, Griot M, Rosenzweig M, et al. · Journal of Veterinary Internal Medicine

Record details

Citation record. A verified article link or abstract is not currently available.

Authors
Giger U, Griot M, Rosenzweig M, et al.
Journal
Journal of Veterinary Internal Medicine
Year
1991
Species / model
Canine (Dog)

SOURCE VERIFICATION REQUIRED. The current repository has not established a sufficiently reliable primary PMID or DOI for this supplied citation. Retain as an unmatched historical bibliography record until the primary source is verified.

Year requires bibliographic review

1990Ovine (Sheep)

Hemodynamic effects and oxygen transport properties of a new blood substitute in a model of massive blood replacement

Vlahakes GJ, Lee R, Jacobs EE Jr, LaRaia PJ, Austen WG · The Journal of Thoracic and Cardiovascular Surgery

Record details
Authors
Vlahakes GJ, Lee R, Jacobs EE Jr, LaRaia PJ, Austen WG
Journal
The Journal of Thoracic and Cardiovascular Surgery
Year
1990
Species / model
Ovine (Sheep)
Author institutions
Massachusetts General Hospital
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.1016/s0022-5223(19)35530-8
PMID
2391974
Original citation
Vlahakes GJ, Lee R, Jacobs EE Jr, LaRaia PJ, Austen WG. Hemodynamic effects and oxygen transport properties of a new blood substitute in a model of massive blood replacement. J Thorac Cardiovasc Surg. 1990 Sep;100(3):379-88.
1989Rodent

Ultrapure, stroma-free, polymerized bovine hemoglobin solution: evaluation of renal toxicity

Lee R, Atsumi N, Jacobs EE Jr, Austen WG, Vlahakes GJ · Journal of Surgical Research

Record details
Authors
Lee R, Atsumi N, Jacobs EE Jr, Austen WG, Vlahakes GJ
Journal
Journal of Surgical Research
Year
1989
Species / model
Rodent
Author institutions
Massachusetts General Hospital
Evidence type
Research Support, Non-U.S. Gov't; Journal Article
DOI
10.1016/0022-4804(89)90092-9
PMID
2811356
Original citation
Lee R, Atsumi N, Jacobs EE Jr, Austen WG, Vlahakes GJ. Ultrapure, stroma-free, polymerized bovine hemoglobin solution: evaluation of renal toxicity. J Surg Res. 1989 Nov;47(5):407-11.

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Historical product findings do not establish the efficacy or approval of a future BHOC formulation. Author affiliations do not imply institutional endorsement. About the catalogue.

Oxyglobin clinical & regulatory evidenceHemopure Expanded Access

Updated 14 October 2026