The Science
Science behind oxygen delivery.
Oxygen delivery is not a single number. It is a physiological chain connecting oxygen loading, hemoglobin-mediated transport, circulation, microcirculation, tissue exchange, cellular sensing and metabolism.
Physiology first
From the lungs to the mitochondria.
Hemoglobin concentration and arterial oxygen saturation are important, but they do not by themselves establish whether oxygen delivery is adequate. Blood flow, vascular regulation, microcirculatory distribution, oxygen affinity, diffusion, extraction and metabolic demand all contribute to the final biological outcome.
Scientific foundationsNobel Foundations of Oxygen, Metabolism & PhysiologyA century of Nobel-recognized discoveries that shaped modern understanding of microcirculation, metabolism, nitric oxide, hypoxia and oxygen sensing.
Explore the scientific foundations ↗ O₂ Oxygen deliveryFrom oxygen carrying to functional deliveryExplore how oxygen-carrying capacity, flow and physiological context influence effective oxygen delivery.
Read the evidence summary ↗Precision Oxygenation
Blood is a system. Oxygen delivery is a function.
BHOC is evaluated within this functional framework. The relevant question is not only how much oxygen can be carried, but whether an oxygen-delivery approach is appropriate to the physiological need, clinical context and evidence available for a specific technology.
This distinction is why the scientific pages on BHOC Therapeutics remain concise while deeper source-linked material is maintained in BHOC-platform.
Source-linked science
Go deeper in BHOC-platform.
Peer-reviewed publications, regulatory records, historical sources and application-specific evidence remain available in the structured BHOC-platform repository.